Heatmap showing the gene mutations identified in five genomic acute erythroleukemia (AEL) subgroups (TP53, TP53-mutated AEL; NPM1, NPM1-mutated AEL; KMT2A, KMT2A-mutated or rearranged AEL; NUP98, AEL with NUP98 rearrangements; DDX41, DDX41-mutated AEL); and ‘other’, lacking a recurrent exclusive mutated gene and/or fusion gene (n = 159 biologically independent samples). Heatmap representative of Fig. 3c of Iacobucci et al. 2019. For each sample the following are displayed: Revised International Prognostic Scoring System (IPSS-R), WHO 2008 and 2016 classifications, chromothripsis status, and gene expression cluster as defined in Iacobucci et al. 2019. Genes (rows) harboring mutations are grouped by functional class. The type of genetic alterations are defined as per legend. Mousing over each instance of a mutation provides further information (sample, mutation type, amino acid change, and gene name). Clicking on each gene symbol opens a GenomePaint view of mutations found within the gene across samples in this cohort. Numbers in parentheses next to each gene symbol indicate the number of samples altered.