Displaying a heatmap showing genomic mutation data for different pediatric cancers (columns); genes (rows) are grouped by functional pathway. The color for each type of genetic alteration is defined as per legend. Mousing over each instance of a mutation provides further information (sample, mutation type, amino acid change, and gene name). Clicking on each gene symbol opens a GenomePaint view of mutations found within the gene across samples in this cohort. Selecting the ‘PIE CHART’ button renders a summary display of the mutations within each cancer subtype (columns) and affected biological pathways (rows). The number of mutations detected in each cancer subtype is represented by a barplot. The representation of each biological pathway among detected mutations within a cancer subtype is illustrated with a pie-graph, in each case showing the proportion of each type of mutation. Numbers in parentheses next to each gene symbol indicate the number of samples altered.