Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma
Children and infants who experienced medulloblastoma relapse donated tumor samples which were analyzed by DNA methylation array and next-generation sequencing. The primary-relapse pairs. The results below are arrayed by subgroup with age, sex and metadata provided. With only a few Group 3 or 4 exceptions relapsed tumors remained true to subgroup. Chromosomal abnormalities are displayed by arm and genetic alterations by selected genes. The degree and pattern of molecular conservation at relapse varies by subgroup.