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The whole-genome landscape of medulloblastoma subtypes

St. Jude Children's Research Hospital

48 4

Jul 19, 2017

PMID 28726821

11.2K

Whole Genome Sequencing

Whole Exome Sequencing

Methylation Array

Displaying a heatmap of recurrent gene mutations found in 433 medulloblastoma patient samples from whole-genome and whole-exome sequencing data. Samples are grouped according to subtype (WNT, SHH, Group 3, Group 4). Ploidy, patient age group (infant, child, or adult), and gender are indicated. Visualization representative of Northcott, et al. 2017, Fig. 2a, 3a,b. Mousing over each instance of a mutation provides further information (sample, mutation type, amino acid change, and gene name). Clicking on each gene symbol opens a ProteinPaint view of mutations found within the gene for this cohort. Numbers next to each gene symbol in parentheses indicate the number of samples altered.

Loading Visualization

runproteinpaint({
  host: "https://proteinpaint.stjude.org",
  holder: visualizationContainer[0],
  nobox: 1,
  noheader: true,
  genome: "hg19",
  studyview: {
    hide_navigation: 1,
    name: "WGS_MB",
    mutationset: [{
      snvindel: "dfinkels/WGS_MB/snv_1.txt"
    }],

    show_heatmap: 1,
    heatmapJSON:{
  		"samplegroup": [
    {
      "name": "WNT",
      "lst": [
        {
          "name": "ICGC_MB256"
        },
        {
          "name": "MD-278"
        },
        {
          "name": "ICGC_MB122"
        },
        {
          "name": "ICGC_MB276"
        },
        {
          "name": "MB_Exm599"
        },
        {
          "name": "ICGC_MB31"
        },
        {
          "name": "MD-290"
        },
        {
          "name": "MDT-AP-1299"
        },
        {
          "name": "SJMB001_D"
        },
        {
          "name": "SJMB040_D"
        },
        {
          "name": "MDT-AP-1368"
        },
        {
          "name": "MD-144"
        },
        {
          "name": "SJMB028_D"
        },
        {
          "name": "ICGC_MB124"
        },
        {
          "name": "MB_Exm987"
        },
        {
          "name": "ICGC_MB130"
        },
        {
          "name": "ICGC_MB140"
        },
        {
          "name": "ICGC_MB148"
        },
        {
          "name": "ICGC_MB176"
        },
        {
          "name": "ICGC_MB46"
        },
        {
          "name": "MD-121"
        },
        {
          "name": "MD-292"
        },
        {
          "name": "ICGC_MB14"
        },
        {
          "name": "ICGC_MB290"
        },
        {
          "name": "ICGC_MB112"
        },
        {
          "name": "ICGC_MB20"
        },
        {
          "name": "MD-279"
        },
        {
          "name": "ICGC_MB128"
        },
        {
          "name": "ICGC_MB242"
        },
        {
          "name": "ICGC_MB107"
        },
        {
          "name": "ICGC_MB117"
        },
        {
          "name": "SJMB041_D"
        },
        {
          "name": "ICGC_MB113"
        },
        {
          "name": "ICGC_MB54"
        },
        {
          "name": "SJMB002_D"
        },
        {
          "name": "ICGC_MB23"
        }
      ]
    },
    {
      "name": "SHH",
      "lst": [
        {
          "name": "ICGC_MB132"
        },
        {
          "name": "ICGC_MB142"
        },
        {
          "name": "ICGC_MB193"
        },
        {
          "name": "ICGC_MB21"
        },
        {
          "name": "ICGC_MB244"
        },
        {
          "name": "ICGC_MB28"
        },
        {
          "name": "ICGC_MB35"
        },
        {
          "name": "MB_Exm250"
        },
        {
          "name": "MD-057"
        },
        {
          "name": "MD-085"
        },
        {
          "name": "MD-095"
        },
        {
          "name": "MD-241"
        },
        {
          "name": "MD-332"
        },
        {
          "name": "MDT-AP-0435"
        },
        {
          "name": "MDT-AP-2006"
        },
        {
          "name": "MDT-AP-2131"
        },
        {
          "name": "MDT-AP-2174"
        },
        {
          "name": "MDT-AP-2712"
        },
        {
          "name": "MDT-AP-3399"
        },
        {
          "name": "MDT-AP-3431"
        },
        {
          "name": "SJMB013_D"
        },
        {
          "name": "ICGC_MB3"
        },
        {
          "name": "MDT-AP-1202"
        },
        {
          "name": "ICGC_MB81"
        },
        {
          "name": "MD-294"
        },
        {
          "name": "ICGC_MB59"
        },
        {
          "name": "ICGC_MB125"
        },
        {
          "name": "ICGC_MB60"
        },
        {
          "name": "ICGC_MB68"
        },
        {
          "name": "MDT-AP-2184"
        },
        {
          "name": "ICGC_MB78"
        },
        {
          "name": "ICGC_MB79"
        },
        {
          "name": "ICGC_MB66"
        },
        {
          "name": "MD-286"
        },
        {
          "name": "ICGC_MB102"
        },
        {
          "name": "MDT-AP-0118"
        },
        {
          "name": "MDT-AP-1137"
        },
        {
          "name": "ICGC_MB75"
        },
        {
          "name": "MB_Exm528"
        },
        {
          "name": "MDT-AP-2112"
        },
        {
          "name": "MDT-AP-0706"
        },
        {
          "name": "ICGC_MB56"
        },
        {
          "name": "MDT-AP-2182"
        },
        {
          "name": "ICGC_MB262"
        },
        {
          "name": "MD-050"
        },
        {
          "name": "MDT-AP-1216"
        },
        {
          "name": "ICGC_MB234"
        },
        {
          "name": "MDT-AP-1217"
        },
        {
          "name": "ICGC_MB246"
        },
        {
          "name": "MDT-AP-0209"
        },
        {
          "name": "ICGC_MB67"
        },
        {
          "name": "ICGC_MB77"
        },
        {
          "name": "ICGC_MB171"
        },
        {
          "name": "ICGC_MB82"
        },
        {
          "name": "ICGC_MB194"
        },
        {
          "name": "ICGC_MB61"
        },
        {
          "name": "ICGC_MB179"
        },
        {
          "name": "ICGC_MB136"
        },
        {
          "name": "ICGC_MB62"
        },
        {
          "name": "MDT-AP-2183"
        },
        {
          "name": "ICGC_MB101"
        },
        {
          "name": "ICGC_MB74"
        },
        {
          "name": "ICGC_MB181"
        },
        {
          "name": "SJMB033_D"
        },
        {
          "name": "ICGC_MB284"
        },
        {
          "name": "ICGC_MB178"
        },
        {
          "name": "MD-237"
        },
        {
          "name": "ICGC_MB180"
        },
        {
          "name": "MDT-AP-1200"
        },
        {
          "name": "ICGC_MB239"
        },
        {
          "name": "ICGC_MB12"
        },
        {
          "name": "ICGC_MB53"
        },
        {
          "name": "MD-306"
        },
        {
          "name": "MD-320"
        },
        {
          "name": "MD-335"
        },
        {
          "name": "MDT-AP-2307"
        },
        {
          "name": "ICGC_MB88"
        },
        {
          "name": "ICGC_MB206"
        },
        {
          "name": "ICGC_LFS_MB1"
        },
        {
          "name": "ICGC_MB137"
        },
        {
          "name": "ICGC_MB145"
        },
        {
          "name": "ICGC_MB159"
        },
        {
          "name": "ICGC_MB250"
        },
        {
          "name": "ICGC_MB275"
        },
        {
          "name": "MDT-AP-1218"
        },
        {
          "name": "SJMB004_D"
        },
        {
          "name": "MDT-AP-1208"
        },
        {
          "name": "MDT-AP-2738"
        },
        {
          "name": "MD-042"
        },
        {
          "name": "ICGC_MB34"
        },
        {
          "name": "MDT-AP-0707"
        },
        {
          "name": "ICGC_LFS_MB2"
        },
        {
          "name": "ICGC_MB243"
        },
        {
          "name": "SJMB003_D"
        },
        {
          "name": "ICGC_MB295"
        },
        {
          "name": "ICGC_MB299"
        },
        {
          "name": "MDT-AP-2077"
        },
        {
          "name": "MDT-AP-0704"
        },
        {
          "name": "ICGC_MB104"
        },
        {
          "name": "ICGC_MB266"
        },
        {
          "name": "ICGC_MB63"
        },
        {
          "name": "MDT-AP-2111"
        },
        {
          "name": "ICGC_MB204"
        },
        {
          "name": "ICGC_MB126"
        },
        {
          "name": "ICGC_MB143"
        },
        {
          "name": "ICGC_MB216"
        },
        {
          "name": "ICGC_MB217"
        },
        {
          "name": "ICGC_MB274"
        },
        {
          "name": "MD-097"
        },
        {
          "name": "SJMB012_D"
        },
        {
          "name": "MDT-AP-2149"
        },
        {
          "name": "ICGC_MB1"
        },
        {
          "name": "ICGC_MB187"
        },
        {
          "name": "ICGC_MB309"
        },
        {
          "name": "MDT-AP-1210"
        },
        {
          "name": "MD-051"
        },
        {
          "name": "MD-330"
        },
        {
          "name": "ICGC_MB155"
        },
        {
          "name": "ICGC_MB167"
        },
        {
          "name": "ICGC_MB214"
        },
        {
          "name": "ICGC_MB268"
        },
        {
          "name": "ICGC_MB287"
        },
        {
          "name": "ICGC_MB307"
        },
        {
          "name": "ICGC_MB37"
        },
        {
          "name": "MD-133"
        },
        {
          "name": "MD-282"
        },
        {
          "name": "MD-329"
        },
        {
          "name": "MDT-AP-0749"
        },
        {
          "name": "MDT-AP-1211"
        },
        {
          "name": "MDT-AP-1348"
        },
        {
          "name": "MDT-AP-2774"
        }
      ]
    },
    {
      "name": "Group 3",
      "lst": [
        {
          "name": "ICGC_MB518"
        },
        {
          "name": "MD-274"
        },
        {
          "name": "ICGC_MB144"
        },
        {
          "name": "MDT-AP-1364"
        },
        {
          "name": "SJMB030_D"
        },
        {
          "name": "MD-143"
        },
        {
          "name": "ICGC_MB226"
        },
        {
          "name": "MD-141"
        },
        {
          "name": "ICGC_MB289"
        },
        {
          "name": "MB_Exm10"
        },
        {
          "name": "MB_Exm1001"
        },
        {
          "name": "MB_Exm516"
        },
        {
          "name": "MB_Exm17"
        },
        {
          "name": "ICGC_MB277"
        },
        {
          "name": "ICGC_MB9"
        },
        {
          "name": "MD-277"
        },
        {
          "name": "MD-284"
        },
        {
          "name": "MDT-AP-2004"
        },
        {
          "name": "ICGC_MB800"
        },
        {
          "name": "ICGC_MB39"
        },
        {
          "name": "MDT-AP-1166"
        },
        {
          "name": "MDT-AP-2452"
        },
        {
          "name": "ICGC_MB151"
        },
        {
          "name": "MD-023"
        },
        {
          "name": "ICGC_MB5"
        },
        {
          "name": "MB_Exm564"
        },
        {
          "name": "ICGC_MB111"
        },
        {
          "name": "ICGC_MB170"
        },
        {
          "name": "ICGC_MB296"
        },
        {
          "name": "ICGC_MB95"
        },
        {
          "name": "MDT-AP-2177"
        },
        {
          "name": "MDT-AP-1298"
        },
        {
          "name": "SJMB010_D"
        },
        {
          "name": "SJMB039_D"
        },
        {
          "name": "ICGC_MB291"
        },
        {
          "name": "MDT-AP-2510"
        },
        {
          "name": "ICGC_MB225"
        },
        {
          "name": "ICGC_MB247"
        },
        {
          "name": "ICGC_MB36"
        },
        {
          "name": "MDT-AP-2559"
        },
        {
          "name": "ICGC_MB106"
        },
        {
          "name": "ICGC_MB190"
        },
        {
          "name": "ICGC_MB50"
        },
        {
          "name": "MD-212"
        },
        {
          "name": "MDT-AP-2631"
        },
        {
          "name": "MBRep_T27"
        },
        {
          "name": "ICGC_MB131"
        },
        {
          "name": "ICGC_MB134"
        },
        {
          "name": "ICGC_MB139"
        },
        {
          "name": "ICGC_MB141"
        },
        {
          "name": "ICGC_MB146"
        },
        {
          "name": "ICGC_MB149"
        },
        {
          "name": "ICGC_MB152"
        },
        {
          "name": "ICGC_MB153"
        },
        {
          "name": "ICGC_MB16"
        },
        {
          "name": "ICGC_MB161"
        },
        {
          "name": "ICGC_MB164"
        },
        {
          "name": "ICGC_MB165"
        },
        {
          "name": "ICGC_MB166"
        },
        {
          "name": "ICGC_MB168"
        },
        {
          "name": "ICGC_MB18"
        },
        {
          "name": "ICGC_MB188"
        },
        {
          "name": "ICGC_MB198"
        },
        {
          "name": "ICGC_MB205"
        },
        {
          "name": "ICGC_MB235"
        },
        {
          "name": "ICGC_MB248"
        },
        {
          "name": "ICGC_MB260"
        },
        {
          "name": "ICGC_MB271"
        },
        {
          "name": "ICGC_MB272"
        },
        {
          "name": "ICGC_MB278"
        },
        {
          "name": "ICGC_MB292"
        },
        {
          "name": "ICGC_MB304"
        },
        {
          "name": "ICGC_MB45"
        },
        {
          "name": "ICGC_MB89"
        },
        {
          "name": "ICGC_MB90"
        },
        {
          "name": "ICGC_MB96"
        },
        {
          "name": "ICGC_MB98"
        },
        {
          "name": "MBRep_T54"
        },
        {
          "name": "MBRep_T67"
        },
        {
          "name": "MBRep_T71"
        },
        {
          "name": "MBRep_T79"
        },
        {
          "name": "MB_Exm702"
        },
        {
          "name": "MD-026"
        },
        {
          "name": "MD-028"
        },
        {
          "name": "MD-034"
        },
        {
          "name": "MD-035"
        },
        {
          "name": "MD-047"
        },
        {
          "name": "MD-054"
        },
        {
          "name": "MD-088"
        },
        {
          "name": "MD-146"
        },
        {
          "name": "MD-208"
        },
        {
          "name": "MD-220"
        },
        {
          "name": "MD-283"
        },
        {
          "name": "MD-285"
        },
        {
          "name": "MD-287"
        },
        {
          "name": "MD-288"
        },
        {
          "name": "MD-289"
        },
        {
          "name": "MD-293"
        },
        {
          "name": "MD-296"
        },
        {
          "name": "MD-324"
        },
        {
          "name": "MD-328"
        },
        {
          "name": "MD-333"
        },
        {
          "name": "MD-334"
        },
        {
          "name": "MD-339"
        },
        {
          "name": "MD-340"
        },
        {
          "name": "MD-341"
        },
        {
          "name": "MD-343"
        },
        {
          "name": "MDT-AP-0207"
        },
        {
          "name": "MDT-AP-1167"
        },
        {
          "name": "MDT-AP-1369"
        },
        {
          "name": "MDT-AP-1402"
        },
        {
          "name": "MDT-AP-2001"
        },
        {
          "name": "MDT-AP-2073"
        },
        {
          "name": "MDT-AP-2110"
        },
        {
          "name": "MDT-AP-2115"
        },
        {
          "name": "MDT-AP-2169"
        },
        {
          "name": "MDT-AP-2173"
        },
        {
          "name": "MDT-AP-2180"
        },
        {
          "name": "MDT-AP-2185"
        },
        {
          "name": "MDT-AP-2405"
        },
        {
          "name": "MDT-AP-2745"
        },
        {
          "name": "MDT-AP-2832"
        },
        {
          "name": "MDT-AP-2963"
        },
        {
          "name": "MDT-AP-3156"
        },
        {
          "name": "MDT-AP-3402"
        },
        {
          "name": "MDT-AP-3417"
        },
        {
          "name": "SJMB006_D"
        },
        {
          "name": "SJMB008_D"
        },
        {
          "name": "SJMB017_D"
        },
        {
          "name": "SJMB025_D"
        },
        {
          "name": "SJMB031_D"
        }
      ]
    },
    {
      "name": "Group 4",
      "lst": [
        {
          "name": "ICGC_MB19"
        },
        {
          "name": "MD-331"
        },
        {
          "name": "ICGC_MB302"
        },
        {
          "name": "ICGC_MB261"
        },
        {
          "name": "MDT-AP-0222"
        },
        {
          "name": "ICGC_MB147"
        },
        {
          "name": "ICGC_MB199"
        },
        {
          "name": "ICGC_MB236"
        },
        {
          "name": "ICGC_MB49"
        },
        {
          "name": "MB_Exm1017"
        },
        {
          "name": "MD-295"
        },
        {
          "name": "MDT-AP-1365"
        },
        {
          "name": "MDT-AP-2178"
        },
        {
          "name": "ICGC_MB280"
        },
        {
          "name": "ICGC_MB249"
        },
        {
          "name": "MB_Exm575"
        },
        {
          "name": "MDT-AP-1367"
        },
        {
          "name": "MDT-AP-2171"
        },
        {
          "name": "ICGC_MB174"
        },
        {
          "name": "ICGC_MB303"
        },
        {
          "name": "MBRep_T38"
        },
        {
          "name": "MB_Exm557"
        },
        {
          "name": "MB_Exm879"
        },
        {
          "name": "SJMB018_D"
        },
        {
          "name": "ICGC_MB224"
        },
        {
          "name": "ICGC_MB285"
        },
        {
          "name": "ICGC_MB288"
        },
        {
          "name": "ICGC_MB32"
        },
        {
          "name": "MBRep_T40"
        },
        {
          "name": "MD-045"
        },
        {
          "name": "MD-318"
        },
        {
          "name": "MDT-AP-2116"
        },
        {
          "name": "MDT-AP-2849"
        },
        {
          "name": "MDT-AP-2878"
        },
        {
          "name": "MDT-AP-2304"
        },
        {
          "name": "ICGC_MB306"
        },
        {
          "name": "ICGC_MB7"
        },
        {
          "name": "MD-305"
        },
        {
          "name": "MD-342"
        },
        {
          "name": "MDT-AP-1366"
        },
        {
          "name": "SJMB029_D"
        },
        {
          "name": "ICGC_MB293"
        },
        {
          "name": "ICGC_MB213"
        },
        {
          "name": "ICGC_MB228"
        },
        {
          "name": "ICGC_MB305"
        },
        {
          "name": "SJMB009_D"
        },
        {
          "name": "ICGC_MB233"
        },
        {
          "name": "ICGC_MB163"
        },
        {
          "name": "MD-142"
        },
        {
          "name": "MDT-AP-2859"
        },
        {
          "name": "ICGC_MB281"
        },
        {
          "name": "SJMB020_D"
        },
        {
          "name": "ICGC_MB265"
        },
        {
          "name": "MDT-AP-0580"
        },
        {
          "name": "MDT-AP-3021"
        },
        {
          "name": "SJMB023_D"
        },
        {
          "name": "SJMB035_D"
        },
        {
          "name": "ICGC_MB99"
        },
        {
          "name": "ICGC_MB185"
        },
        {
          "name": "ICGC_MB8"
        },
        {
          "name": "MDT-AP-1168"
        },
        {
          "name": "SJMB011_D"
        },
        {
          "name": "MD-127"
        },
        {
          "name": "ICGC_MB58"
        },
        {
          "name": "ICGC_MB119"
        },
        {
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      "Age": "infant",
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      "Gender": "f"
    },
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      "Age": "infant",
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      "Gender": "f"
    },
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      "Age": "infant",
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      "Gender": "f"
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      "Age": "child",
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      "Gender": "m"
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      "Age": "child",
      "Ploidy": "hyperploid",
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      "Age": "infant",
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      "Gender": "m"
    },
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      "Age": "child",
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    },
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      "Age": "infant",
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    },
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      "Age": "infant",
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    },
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      "Age": "adult",
      "Ploidy": "diploid",
      "Gender": "f"
    },
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      "Age": "adult",
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      "Gender": "f"
    },
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      "Age": "adult",
      "Ploidy": "diploid",
      "Gender": "f"
    },
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      "Age": "adult",
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    },
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      "Age": "adult",
      "Ploidy": "diploid",
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    },
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      "Age": "adult",
      "Ploidy": "diploid",
      "Gender": "f"
    },
    "ICGC_MB60": {
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      "Age": "adult",
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    },
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      "Age": "adult",
      "Ploidy": "diploid",
      "Gender": "f"
    },
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      "Age": "adult",
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    },
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      "Age": "adult",
      "Ploidy": "diploid",
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    },
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      "Age": "adult",
      "Ploidy": "diploid",
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    },
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      "Age": "adult",
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    },
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    },
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      "Age": "adult",
      "Ploidy": "diploid",
      "Gender": "t"
    },
    "MDT-AP-0118": {
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      "Age": "child",
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      "Age": "infant",
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    },
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      "Age": "adult",
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    },
    "MB_Exm528": {
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      "Age": "infant",
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      "Gender": "f"
    },
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      "Age": "infant",
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    },
    "MDT-AP-0706": {
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      "Age": "adult",
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    },
    "ICGC_MB56": {
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      "Age": "adult",
      "Ploidy": "diploid",
      "Gender": "na"
    },
    "MDT-AP-2182": {
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      "Age": "adult",
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    },
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      "Age": "adult",
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    },
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      "Age": "infant",
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      "Gender": "f"
    },
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      "Age": "child",
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    },
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      "Age": "adult",
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    },
    "ICGC_MB246": {
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      "Age": "adult",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MDT-AP-0209": {
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      "Age": "child",
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    },
    "ICGC_MB77": {
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      "Age": "adult",
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    },
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    },
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      "Age": "adult",
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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      "Age": "adult",
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    },
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    },
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    },
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    "MDT-AP-1200": {
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    },
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      "Age": "adult",
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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      "Age": "adult",
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    },
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    },
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      "Age": "adult",
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    },
    "MDT-AP-2111": {
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      "Age": "adult",
      "Ploidy": "diploid",
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    },
    "ICGC_MB126": {
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      "Age": "adult",
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    },
    "ICGC_MB143": {
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      "Age": "adult",
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    },
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      "Age": "na",
      "Ploidy": "diploid",
      "Gender": "t"
    },
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      "Age": "na",
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    },
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      "Age": "infant",
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    },
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    },
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    },
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      "Age": "child",
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    },
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      "Age": "infant",
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    },
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    },
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    },
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    },
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    },
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      "Age": "infant",
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    },
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      "Age": "child",
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    },
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      "Age": "na",
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    },
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      "Age": "infant",
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    },
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      "Age": "infant",
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    },
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      "Age": "na",
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    },
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      "Age": "infant",
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    },
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    },
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    },
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    },
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    },
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      "Age": "infant",
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    },
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      "Age": "child",
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    },
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      "Gender": "m"
    },
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      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "f"
    },
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      "Ploidy": "hyperploid",
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    },
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      "Age": "child",
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    },
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      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
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      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "m"
    },
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      "Gender": "m"
    },
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      "Age": "child",
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    },
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      "Age": "infant",
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    },
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      "Age": "child",
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      "Gender": "m"
    },
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      "Age": "infant",
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      "Gender": "f"
    },
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      "Age": "child",
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      "Gender": "m"
    },
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      "Age": "child",
      "Ploidy": "diploid",
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    },
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      "Age": "child",
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    },
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      "Age": "child",
      "Ploidy": "na",
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    },
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      "Age": "child",
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      "Gender": "m"
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      "Age": "child",
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    },
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      "Age": "child",
      "Ploidy": "na",
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    },
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      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "m"
    },
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      "Age": "child",
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      "Age": "child",
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      "Age": "child",
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    },
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      "Gender": "f"
    },
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      "Age": "child",
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    },
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      "Age": "child",
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      "Gender": "m"
    },
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      "Age": "child",
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    },
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      "Age": "adult",
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    },
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    },
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      "Age": "infant",
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      "Age": "child",
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    },
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      "Age": "child",
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    },
    "MDT-AP-2510": {
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      "Age": "child",
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    },
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      "Age": "child",
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    },
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    },
    "MDT-AP-2559": {
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    },
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      "Age": "infant",
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    },
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    },
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    },
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      "Age": "child",
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      "Age": "child",
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    },
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      "Age": "infant",
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      "Age": "infant",
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      "Gender": "k"
    },
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    },
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    },
    "ICGC_MB149": {
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      "Age": "na",
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      "Gender": "m"
    },
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    },
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      "Age": "infant",
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      "Age": "infant",
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    },
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      "Age": "child",
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      "Age": "child",
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    },
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      "Age": "child",
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    },
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      "Age": "child",
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    },
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      "Age": "child",
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    },
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      "Age": "child",
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    },
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      "Age": "infant",
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      "Age": "child",
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    },
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      "Age": "infant",
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      "Age": "child",
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      "Age": "child",
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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      "Gender": "na"
    },
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    },
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    },
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      "Gender": "f"
    },
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    },
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      "Ploidy": "na",
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    },
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    },
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    },
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      "Age": "adult",
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    },
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      "Age": "child",
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    },
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    },
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      "Gender": "m"
    },
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    },
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    },
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      "Gender": "f"
    },
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      "Age": "child",
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      "Gender": "m"
    },
    "MDT-AP-0207": {
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      "Age": "child",
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    },
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    },
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      "Ploidy": "diploid",
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    },
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    },
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    },
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    },
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    },
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      "Age": "child",
      "Ploidy": "diploid",
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    },
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      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "ICGC_MB85": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "f"
    },
    "ICGC_MB86": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "ICGC_MB92": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "ICGC_MB94": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "f"
    },
    "MBRep_T36": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "m"
    },
    "MBRep_T41": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "f"
    },
    "MBRep_T70": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MBRep_T72": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "m"
    },
    "MB_Exm23": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MB_Exm704": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-021": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-022": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-053": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "f"
    },
    "MD-074": {
      "WGS": "0",
      "WES": "1",
      "Age": "infant",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-093": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-204": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-206": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "f"
    },
    "MD-207": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-243": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-253": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "f"
    },
    "MD-275": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-280": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-281": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "f"
    },
    "MD-304": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-336": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-337": {
      "WGS": "0",
      "WES": "1",
      "Age": "infant",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MD-338": {
      "WGS": "0",
      "WES": "1",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MDT-AP-0009": {
      "WGS": "1",
      "WES": "0",
      "Age": "infant",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-0074": {
      "WGS": "1",
      "WES": "0",
      "Age": "infant",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-0220": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "f"
    },
    "MDT-AP-0223": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "f"
    },
    "MDT-AP-0432": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-0437": {
      "WGS": "1",
      "WES": "0",
      "Age": "infant",
      "Ploidy": "diploid",
      "Gender": "m"
    },
    "MDT-AP-0530": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-0705": {
      "WGS": "1",
      "WES": "0",
      "Age": "adult",
      "Ploidy": "diploid",
      "Gender": "m"
    },
    "MDT-AP-1165": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-1206": {
      "WGS": "1",
      "WES": "0",
      "Age": "infant",
      "Ploidy": "hyperploid",
      "Gender": "f"
    },
    "MDT-AP-1207": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "m"
    },
    "MDT-AP-1209": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-1323": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-1362": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-1403": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-1405": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "m"
    },
    "MDT-AP-2075": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "f"
    },
    "MDT-AP-2123": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "m"
    },
    "MDT-AP-2130": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-2148": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-2407": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "m"
    },
    "MDT-AP-2514": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "f"
    },
    "MDT-AP-2532": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-2562": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "m"
    },
    "MDT-AP-2673": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "f"
    },
    "MDT-AP-2814": {
      "WGS": "1",
      "WES": "0",
      "Age": "adult",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-3017": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "f"
    },
    "MDT-AP-3019": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "na",
      "Gender": "m"
    },
    "MDT-AP-3020": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "MDT-AP-3401": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "m"
    },
    "SJMB014_D": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "SJMB016_D": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "f"
    },
    "SJMB019_D": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "SJMB024_D": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "SJMB026_D": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "f"
    },
    "SJMB027_D": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "SJMB032_D": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "diploid",
      "Gender": "f"
    },
    "SJMB034_D": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "SJMB036_D": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "f"
    },
    "SJMB037_D": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    },
    "SJMB038_D": {
      "WGS": "1",
      "WES": "0",
      "Age": "child",
      "Ploidy": "hyperploid",
      "Gender": "m"
    }
  },
  "metadata": [
    {
      "name": "WGS",
      "lst": [],
      "setkey": "Assay",
      "label": "WGS",
      "key": "WGS",
      "values": {
        "0": "#aec7e8",
        "1": "#1f77b4",
        "undefined": ""
      },
      "renderAs": "",
      "colorRange": null,
      "sortorder": 0,
      "hasOnlyNumericVals": false,
      "colorScale": null
    },
    {
      "name": "WES",
      "lst": [],
      "setkey": "Assay",
      "label": "WES",
      "key": "WES",
      "values": {
        "0": "#aec7e8",
        "1": "#1f77b4",
        "undefined": ""
      },
      "renderAs": "",
      "colorRange": null,
      "sortorder": 0,
      "hasOnlyNumericVals": false,
      "colorScale": null
    },
    {
      "name": "Age",
      "lst": [],
      "setkey": "Age",
      "label": "Age",
      "key": "Age",
      "values": {
        "undefined": "",
        "na": "#ff7f0e",
        "child": "#ffbb78",
        "adult": "#2ca02c",
        "infant": "#98df8a"
      },
      "renderAs": "",
      "colorRange": null,
      "sortorder": 0,
      "hasOnlyNumericVals": false,
      "colorScale": null
    },
    {
      "name": "Ploidy",
      "lst": [],
      "setkey": "Ploidy",
      "label": "Ploidy",
      "key": "Ploidy",
      "values": {
        "undefined": "",
        "hyperploid": "#d62728",
        "na": "#ff7f0e",
        "diploid": "#ff9896"
      },
      "renderAs": "",
      "colorRange": null,
      "sortorder": 0,
      "hasOnlyNumericVals": false,
      "colorScale": null
    },
    {
      "name": "Gender",
      "lst": [],
      "setkey": "Gender",
      "label": "Gender",
      "key": "Gender",
      "values": {
        "undefined": "",
        "m": "#9467bd",
        "f": "#c5b0d5",
        "t": "#8c564b",
        "na": "#ff7f0e",
        "k": "#c49c94"
      },
      "renderAs": "",
      "colorRange": null,
      "sortorder": 0,
      "hasOnlyNumericVals": false,
      "colorScale": null
    }
  ],
  "metabarNames": []
	}
   }
})

Visualization Code

runproteinpaint({
  host: "https://proteinpaint.stjude.org",
  holder: visualizationContainer[0],
  nobox: 1,
  noheader: true,
  genome: "hg19",
  studyview: {
    hide_navigation: 1,
    name: "WGS_MB",
    mutationset: [{
      snvindel: "dfinkels/WGS_MB/snv_1.txt"
    }],

    show_heatmap: 1,
    heatmapJSON:{
  		"samplegroup": [
    {
      "name": "WNT",
      "lst": [
        {
          "name": "ICGC_MB256"
        },
        {
          "name": "MD-278"
        },
        {
          "name": "ICGC_MB122"
        },
        {
          "name": "ICGC_MB276"
        },
        {
          "name": "MB_Exm599"
        },
        {
          "name": "ICGC_MB31"
        },
        {
          "name": "MD-290"
        },
        {
          "name": "MDT-AP-1299"
        },
        {
          "name": "SJMB001_D"
        },
        {
          "name": "SJMB040_D"
        },
        {
          "name": "MDT-AP-1368"
        },
        {
          "name": "MD-144"
        },
        {
          "name": "SJMB028_D"
        },
        {
          "name": "ICGC_MB124"
        },
        {
          "name": "MB_Exm987"
        },
        {
          "name": "ICGC_MB130"
        },
        {
          "name": "ICGC_MB140"
        },
        {
          "name": "ICGC_MB148"
        },
        {
          "name": "ICGC_MB176"
        },
        {
          "name": "ICGC_MB46"
        },
        {
          "name": "MD-121"
        },
        {
          "name": "MD-292"
        },
        {
          "name": "ICGC_MB14"
        },
        {
          "name": "ICGC_MB290"
        },
        {
          "name": "ICGC_MB112"
        },
        {
          "name": "ICGC_MB20"
        },
        {
          "name": "MD-279"
        },
        {
          "name": "ICGC_MB128"
        },
        {
          "name": "ICGC_MB242"
        },
        {
          "name": "ICGC_MB107"
        },
        {
          "name": "ICGC_MB117"
        },
        {
          "name": "SJMB041_D"
        },
        {
          "name": "ICGC_MB113"
        },
        {
          "name": "ICGC_MB54"
        },
        {
          "name": "SJMB002_D"
        },
        {
          "name": "ICGC_MB23"
        }
      ]
    },
    {
      "name": "SHH",
      "lst": [
        {
          "name": "ICGC_MB132"
        },
        {
          "name": "ICGC_MB142"
        },
        {
          "name": "ICGC_MB193"
        },
        {
          "name": "ICGC_MB21"
        },
        {
          "name": "ICGC_MB244"
        },
        {
          "name": "ICGC_MB28"
        },
        {
          "name": "ICGC_MB35"
        },
        {
          "name": "MB_Exm250"
        },
        {
          "name": "MD-057"
        },
        {
          "name": "MD-085"
        },
        {
          "name": "MD-095"
        },
        {
          "name": "MD-241"
        },
        {
          "name": "MD-332"
        },
        {
          "name": "MDT-AP-0435"
        },
        {
          "name": "MDT-AP-2006"
        },
        {
          "name": "MDT-AP-2131"
        },
        {
          "name": "MDT-AP-2174"
        },
        {
          "name": "MDT-AP-2712"
        },
        {
          "name": "MDT-AP-3399"
        },
        {
          "name": "MDT-AP-3431"
        },
        {
          "name": "SJMB013_D"
        },
        {
          "name": "ICGC_MB3"
        },
        {
          "name": "MDT-AP-1202"
        },
        {
          "name": "ICGC_MB81"
        },
        {
          "name": "MD-294"
        },
        {
          "name": "ICGC_MB59"
        },
        {
          "name": "ICGC_MB125"
        },
        {
          "name": "ICGC_MB60"
        },
        {
          "name": "ICGC_MB68"
        },
        {
          "name": "MDT-AP-2184"
        },
        {
          "name": "ICGC_MB78"
        },
        {
          "name": "ICGC_MB79"
        },
        {
          "name": "ICGC_MB66"
        },
        {
          "name": "MD-286"
        },
        {
          "name": "ICGC_MB102"
        },
        {
          "name": "MDT-AP-0118"
        },
        {
          "name": "MDT-AP-1137"
        },
        {
          "name": "ICGC_MB75"
        },
        {
          "name": "MB_Exm528"
        },
        {
          "name": "MDT-AP-2112"
        },
        {
          "name": "MDT-AP-0706"
        },
        {
          "name": "ICGC_MB56"
        },
        {
          "name": "MDT-AP-2182"
        },
        {
          "name": "ICGC_MB262"
        },
        {
          "name": "MD-050"
        },
        {
          "name": "MDT-AP-1216"
        },
        {
          "name": "ICGC_MB234"
        },
        {
          "name": "MDT-AP-1217"
        },
        {
          "name": "ICGC_MB246"
        },
        {
          "name": "MDT-AP-0209"
        },
        {
          "name": "ICGC_MB67"
        },
        {
          "name": "ICGC_MB77"
        },
        {
          "name": "ICGC_MB171"
        },
        {
          "name": "ICGC_MB82"
        },
        {
          "name": "ICGC_MB194"
        },
        {
          "name": "ICGC_MB61"
        },
        {
          "name": "ICGC_MB179"
        },
        {
          "name": "ICGC_MB136"
        },
        {
          "name": "ICGC_MB62"
        },
        {
          "name": "MDT-AP-2183"
        },
        {
          "name": "ICGC_MB101"
        },
        {
          "name": "ICGC_MB74"
        },
        {
          "name": "ICGC_MB181"
        },
        {
          "name": "SJMB033_D"
        },
        {
          "name": "ICGC_MB284"
        },
        {
          "name": "ICGC_MB178"
        },
        {
          "name": "MD-237"
        },
        {
          "name": "ICGC_MB180"
        },
        {
          "name": "MDT-AP-1200"
        },
        {
          "name": "ICGC_MB239"
        },
        {
          "name": "ICGC_MB12"
        },
        {
          "name": "ICGC_MB53"
        },
        {
          "name": "MD-306"
        },
        {
          "name": "MD-320"
        },
        {
          "name": "MD-335"
        },
        {
          "name": "MDT-AP-2307"
        },
        {
          "name": "ICGC_MB88"
        },
        {
          "name": "ICGC_MB206"
        },
        {
          "name": "ICGC_LFS_MB1"
        },
        {
          "name": "ICGC_MB137"
        },
        {
          "name": "ICGC_MB145"
        },
        {
          "name": "ICGC_MB159"
        },
        {
          "name": "ICGC_MB250"
        },
        {
          "name": "ICGC_MB275"
        },
        {
          "name": "MDT-AP-1218"
        },
        {
          "name": "SJMB004_D"
        },
        {
          "name": "MDT-AP-1208"
        },
        {
          "name": "MDT-AP-2738"
        },
        {
          "name": "MD-042"
        },
        {
          "name": "ICGC_MB34"
        },
        {
          "name": "MDT-AP-0707"
        },
        {
          "name": "ICGC_LFS_MB2"
        },
        {
          "name": "ICGC_MB243"
        },
        {
          "name": "SJMB003_D"
        },
        {
          "name": "ICGC_MB295"
        },
        {
          "name": "ICGC_MB299"
        },
        {
          "name": "MDT-AP-2077"
        },
        {
          "name": "MDT-AP-0704"
        },
        {
          "name": "ICGC_MB104"
        },
        {
          "name": "ICGC_MB266"
        },
        {
          "name": "ICGC_MB63"
        },
        {
          "name": "MDT-AP-2111"
        },
        {
          "name": "ICGC_MB204"
        },
        {
          "name": "ICGC_MB126"
        },
        {
          "name": "ICGC_MB143"
        },
        {
          "name": "ICGC_MB216"
        },
        {
          "name": "ICGC_MB217"
        },
        {
          "name": "ICGC_MB274"
        },
        {
          "name": "MD-097"
        },
        {
          "name": "SJMB012_D"
        },
        {
          "name": "MDT-AP-2149"
        },
        {
          "name": "ICGC_MB1"
        },
        {
          "name": "ICGC_MB187"
        },
        {
          "name": "ICGC_MB309"
        },
        {
          "name": "MDT-AP-1210"
        },
        {
          "name": "MD-051"
        },
        {
          "name": "MD-330"
        },
        {
          "name": "ICGC_MB155"
        },
        {
          "name": "ICGC_MB167"
        },
        {
          "name": "ICGC_MB214"
        },
        {
          "name": "ICGC_MB268"
        },
        {
          "name": "ICGC_MB287"
        },
        {
          "name": "ICGC_MB307"
        },
        {
          "name": "ICGC_MB37"
        },
        {
          "name": "MD-133"
        },
        {
          "name": "MD-282"
        },
        {
          "name": "MD-329"
        },
        {
          "name": "MDT-AP-0749"
        },
        {
          "name": "MDT-AP-1211"
        },
        {
          "name": "MDT-AP-1348"
        },
        {
          "name": "MDT-AP-2774"
        }
      ]
    },
    {
      "name": "Group 3",
      "lst": [
        {
          "name": "ICGC_MB518"
        },
        {
          "name": "MD-274"
        },
        {
          "name": "ICGC_MB144"
        },
        {
          "name": "MDT-AP-1364"
        },
        {
          "name": "SJMB030_D"
        },
        {
          "name": "MD-143"
        },
        {
          "name": "ICGC_MB226"
        },
        {
          "name": "MD-141"
        },
        {
          "name": "ICGC_MB289"
        },
        {
          "name": "MB_Exm10"
        },
        {
          "name": "MB_Exm1001"
        },
        {
          "name": "MB_Exm516"
        },
        {
          "name": "MB_Exm17"
        },
        {
          "name": "ICGC_MB277"
        },
        {
          "name": "ICGC_MB9"
        },
        {
          "name": "MD-277"
        },
        {
          "name": "MD-284"
        },
        {
          "name": "MDT-AP-2004"
        },
        {
          "name": "ICGC_MB800"
        },
        {
          "name": "ICGC_MB39"
        },
        {
          "name": "MDT-AP-1166"
        },
        {
          "name": "MDT-AP-2452"
        },
        {
          "name": "ICGC_MB151"
        },
        {
          "name": "MD-023"
        },
        {
          "name": "ICGC_MB5"
        },
        {
          "name": "MB_Exm564"
        },
        {
          "name": "ICGC_MB111"
        },
        {
          "name": "ICGC_MB170"
        },
        {
          "name": "ICGC_MB296"
        },
        {
          "name": "ICGC_MB95"
        },
        {
          "name": "MDT-AP-2177"
        },
        {
          "name": "MDT-AP-1298"
        },
        {
          "name": "SJMB010_D"
        },
        {
          "name": "SJMB039_D"
        },
        {
          "name": "ICGC_MB291"
        },
        {
          "name": "MDT-AP-2510"
        },
        {
          "name": "ICGC_MB225"
        },
        {
          "name": "ICGC_MB247"
        },
        {
          "name": "ICGC_MB36"
        },
        {
          "name": "MDT-AP-2559"
        },
        {
          "name": "ICGC_MB106"
        },
        {
          "name": "ICGC_MB190"
        },
        {
          "name": "ICGC_MB50"
        },
        {
          "name": "MD-212"
        },
        {
          "name": "MDT-AP-2631"
        },
        {
          "name": "MBRep_T27"
        },
        {
          "name": "ICGC_MB131"
        },
        {
          "name": "ICGC_MB134"
        },
        {
          "name": "ICGC_MB139"
        },
        {
          "name": "ICGC_MB141"
        },
        {
          "name": "ICGC_MB146"
        },
        {
          "name": "ICGC_MB149"
        },
        {
          "name": "ICGC_MB152"
        },
        {
          "name": "ICGC_MB153"
        },
        {
          "name": "ICGC_MB16"
        },
        {
          "name": "ICGC_MB161"
        },
        {
          "name": "ICGC_MB164"
        },
        {
          "name": "ICGC_MB165"
        },
        {
          "name": "ICGC_MB166"
        },
        {
          "name": "ICGC_MB168"
        },
        {
          "name": "ICGC_MB18"
        },
        {
          "name": "ICGC_MB188"
        },
        {
          "name": "ICGC_MB198"
        },
        {
          "name": "ICGC_MB205"
        },
        {
          "name": "ICGC_MB235"
        },
        {
          "name": "ICGC_MB248"
        },
        {
          "name": "ICGC_MB260"
        },
        {
          "name": "ICGC_MB271"
        },
        {
          "name": "ICGC_MB272"
        },
        {
          "name": "ICGC_MB278"
        },
        {
          "name": "ICGC_MB292"
        },
        {
          "name": "ICGC_MB304"
        },
        {
          "name": "ICGC_MB45"
        },
        {
          "name": "ICGC_MB89"
        },
        {
          "name": "ICGC_MB90"
        },
        {
          "name": "ICGC_MB96"
        },
        {
          "name": "ICGC_MB98"
        },
        {
          "name": "MBRep_T54"
        },
        {
          "name": "MBRep_T67"
        },
        {
          "name": "MBRep_T71"
        },
        {
          "name": "MBRep_T79"
        },
        {
          "name": "MB_Exm702"
        },
        {
          "name": "MD-026"
        },
        {
          "name": "MD-028"
        },
        {
          "name": "MD-034"
        },
        {
          "name": "MD-035"
        },
        {
          "name": "MD-047"
        },
        {
          "name": "MD-054"
        },
        {
          "name": "MD-088"
        },
        {
          "name": "MD-146"
        },
        {
          "name": "MD-208"
        },
        {
          "name": "MD-220"
        },
        {
          "name": "MD-283"
        },
        {
          "name": "MD-285"
        },
        {
          "name": "MD-287"
        },
        {
          "name": "MD-288"
        },
        {
          "name": "MD-289"
        },
        {
          "name": "MD-293"
        },
        {
          "name": "MD-296"
        },
        {
          "name": "MD-324"
        },
        {
          "name": "MD-328"
        },
        {
          "name": "MD-333"
        },
        {
          "name": "MD-334"
        },
        {
          "name": "MD-339"
        },
        {
          "name": "MD-340"
        },
        {
          "name": "MD-341"
        },
        {
          "name": "MD-343"
        },
        {
          "name": "MDT-AP-0207"
        },
        {
          "name": "MDT-AP-1167"
        },
        {
          "name": "MDT-AP-1369"
        },
        {
          "name": "MDT-AP-1402"
        },
        {
          "name": "MDT-AP-2001"
        },
        {
          "name": "MDT-AP-2073"
        },
        {
          "name": "MDT-AP-2110"
        },
        {
          "name": "MDT-AP-2115"
        },
        {
          "name": "MDT-AP-2169"
        },
        {
          "name": "MDT-AP-2173"
        },
        {
          "name": "MDT-AP-2180"
        },
        {
          "name": "MDT-AP-2185"
        },
        {
          "name": "MDT-AP-2405"
        },
        {
          "name": "MDT-AP-2745"
        },
        {
          "name": "MDT-AP-2832"
        },
        {
          "name": "MDT-AP-2963"
        },
        {
          "name": "MDT-AP-3156"
        },
        {
          "name": "MDT-AP-3402"
        },
        {
          "name": "MDT-AP-3417"
        },
        {
          "name": "SJMB006_D"
        },
        {
          "name": "SJMB008_D"
        },
        {
          "name": "SJMB017_D"
        },
        {
          "name": "SJMB025_D"
        },
        {
          "name": "SJMB031_D"
        }
      ]
    },
    {
      "name": "Group 4",
      "lst": [
        {
          "name": "ICGC_MB19"
        },
        {
          "name": "MD-331"
        },
        {
          "name": "ICGC_MB302"
        },
        {
          "name": "ICGC_MB261"
        },
        {
          "name": "MDT-AP-0222"
        },
        {
          "name": "ICGC_MB147"
        },
        {
          "name": "ICGC_MB199"
        },
        {
          "name": "ICGC_MB236"
        },
        {
          "name": "ICGC_MB49"
        },
        {
          "name": "MB_Exm1017"
        },
        {
          "name": "MD-295"
        },
        {
          "name": "MDT-AP-1365"
        },
        {
          "name": "MDT-AP-2178"
        },
        {
          "name": "ICGC_MB280"
        },
        {
          "name": "ICGC_MB249"
        },
        {
          "name": "MB_Exm575"
        },
        {
          "name": "MDT-AP-1367"
        },
        {
          "name": "MDT-AP-2171"
        },
        {
          "name": "ICGC_MB174"
        },
        {
          "name": "ICGC_MB303"
        },
        {
          "name": "MBRep_T38"
        },
        {
          "name": "MB_Exm557"
        },
        {
          "name": "MB_Exm879"
        },
        {
          "name": "SJMB018_D"
        },
        {
          "name": "ICGC_MB224"
        },
        {
          "name": "ICGC_MB285"
        },
        {
          "name": "ICGC_MB288"
        },
        {
          "name": "ICGC_MB32"
        },
        {
          "name": "MBRep_T40"
        },
        {
          "name": "MD-045"
        },
        {
          "name": "MD-318"
        },
        {
          "name": "MDT-AP-2116"
        },
        {
          "name": "MDT-AP-2849"
        },
        {
          "name": "MDT-AP-2878"
        },
        {
          "name": "MDT-AP-2304"
        },
        {
          "name": "ICGC_MB306"
        },
        {
          "name": "ICGC_MB7"
        },
        {
          "name": "MD-305"
        },
        {
          "name": "MD-342"
        },
        {
          "name": "MDT-AP-1366"
        },
        {
          "name": "SJMB029_D"
        },
        {
          "name": "ICGC_MB293"
        },
        {
          "name": "ICGC_MB213"
        },
        {
          "name": "ICGC_MB228"
        },
        {
          "name": "ICGC_MB305"
        },
        {
          "name": "SJMB009_D"
        },
        {
          "name": "ICGC_MB233"
        },
        {
          "name": "ICGC_MB163"
        },
        {
          "name": "MD-142"
        },
        {
          "name": "MDT-AP-2859"
        },
        {
          "name": "ICGC_MB281"
        },
        {
          "name": "SJMB020_D"
        },
        {
          "name": "ICGC_MB265"
        },
        {
          "name": "MDT-AP-0580"
        },
        {
          "name": "MDT-AP-3021"
        },
        {
          "name": "SJMB023_D"
        },
        {
          "name": "SJMB035_D"
        },
        {
          "name": "ICGC_MB99"
        },
        {
          "name": "ICGC_MB185"
        },
        {
          "name": "ICGC_MB8"
        },
        {
          "name": "MDT-AP-1168"
        },
        {
          "name": "SJMB011_D"
        },
        {
          "name": "MD-127"
        },
        {
          "name": "ICGC_MB58"
        },
        {
          "name": "ICGC_MB119"
        },
        {
          "name": "ICGC_MB229"
        },
        {
          "name": "MDT-AP-2151"
        },
        {
          "name": "MDT-AP-2181"
        },
        {
          "name": "MDT-AP-2719"
        },
        {
          "name": "MD-090"
        },
        {
          "name": "MDT-AP-2254"
        },
        {
          "name": "MB_Exm645"
        },
        {
          "name": "MDT-AP-1398"
        },
        {
          "name": "SJMB015_D"
        },
        {
          "name": "ICGC_MB279"
        },
        {
          "name": "ICGC_MB184"
        },
        {
          "name": "ICGC_MB91"
        },
        {
          "name": "MD-076"
        },
        {
          "name": "ICGC_MB108"
        },
        {
          "name": "ICGC_MB110"
        },
        {
          "name": "ICGC_MB114"
        },
        {
          "name": "ICGC_MB115"
        },
        {
          "name": "ICGC_MB118"
        },
        {
          "name": "ICGC_MB121"
        },
        {
          "name": "ICGC_MB129"
        },
        {
          "name": "ICGC_MB15"
        },
        {
          "name": "ICGC_MB154"
        },
        {
          "name": "ICGC_MB157"
        },
        {
          "name": "ICGC_MB160"
        },
        {
          "name": "ICGC_MB175"
        },
        {
          "name": "ICGC_MB177"
        },
        {
          "name": "ICGC_MB183"
        },
        {
          "name": "ICGC_MB189"
        },
        {
          "name": "ICGC_MB2"
        },
        {
          "name": "ICGC_MB208"
        },
        {
          "name": "ICGC_MB211"
        },
        {
          "name": "ICGC_MB227"
        },
        {
          "name": "ICGC_MB230"
        },
        {
          "name": "ICGC_MB232"
        },
        {
          "name": "ICGC_MB237"
        },
        {
          "name": "ICGC_MB24"
        },
        {
          "name": "ICGC_MB240"
        },
        {
          "name": "ICGC_MB241"
        },
        {
          "name": "ICGC_MB252"
        },
        {
          "name": "ICGC_MB26"
        },
        {
          "name": "ICGC_MB264"
        },
        {
          "name": "ICGC_MB269"
        },
        {
          "name": "ICGC_MB270"
        },
        {
          "name": "ICGC_MB282"
        },
        {
          "name": "ICGC_MB286"
        },
        {
          "name": "ICGC_MB294"
        },
        {
          "name": "ICGC_MB297"
        },
        {
          "name": "ICGC_MB38"
        },
        {
          "name": "ICGC_MB40"
        },
        {
          "name": "ICGC_MB51"
        },
        {
          "name": "ICGC_MB57"
        },
        {
          "name": "ICGC_MB6"
        },
        {
          "name": "ICGC_MB612"
        },
        {
          "name": "ICGC_MB64"
        },
        {
          "name": "ICGC_MB65"
        },
        {
          "name": "ICGC_MB70"
        },
        {
          "name": "ICGC_MB71"
        },
        {
          "name": "ICGC_MB76"
        },
        {
          "name": "ICGC_MB83"
        },
        {
          "name": "ICGC_MB84"
        },
        {
          "name": "ICGC_MB85"
        },
        {
          "name": "ICGC_MB86"
        },
        {
          "name": "ICGC_MB92"
        },
        {
          "name": "ICGC_MB94"
        },
        {
          "name": "MBRep_T36"
        },
        {
          "name": "MBRep_T41"
        },
        {
          "name": "MBRep_T70"
        },
        {
          "name": "MBRep_T72"
        },
        {
          "name": "MB_Exm23"
        },
        {
          "name": "MB_Exm704"
        },
        {
          "name": "MD-021"
        },
        {
          "name": "MD-022"
        },
        {
          "name": "MD-053"
        },
        {
          "name": "MD-074"
        },
        {
          "name": "MD-093"
        },
        {
          "name": "MD-204"
        },
        {
          "name": "MD-206"
        },
        {
          "name": "MD-207"
        },
        {
          "name": "MD-243"
        },
        {
          "name": "MD-253"
        },
        {
          "name": "MD-275"
        },
        {
          "name": "MD-280"
        },
        {
          "name": "MD-281"
        },
        {
          "name": "MD-304"
        },
        {
          "name": "MD-336"
        },
        {
          "name": "MD-337"
        },
        {
          "name": "MD-338"
        },
        {
          "name": "MDT-AP-0009"
        },
        {
          "name": "MDT-AP-0074"
        },
        {
          "name": "MDT-AP-0220"
        },
        {
          "name": "MDT-AP-0223"
        },
        {
          "name": "MDT-AP-0432"
        },
        {
          "name": "MDT-AP-0437"
        },
        {
          "name": "MDT-AP-0530"
        },
        {
          "name": "MDT-AP-0705"
        },
        {
          "name": "MDT-AP-1165"
        },
        {
          "name": "MDT-AP-1206"
        },
        {
          "name": "MDT-AP-1207"
        },
        {
          "name": "MDT-AP-1209"
        },
        {
          "name": "MDT-AP-1323"
        },
        {
          "name": "MDT-AP-1362"
        },
        {
          "name": "MDT-AP-1403"
        },
        {
          "name": "MDT-AP-1405"
        },
        {
          "name": "MDT-AP-2075"
        },
        {
          "name": "MDT-AP-2123"
        },
        {
          "name": "MDT-AP-2130"
        },
        {
          "name": "MDT-AP-2148"
        },
        {
          "name": "MDT-AP-2407"
        },
        {
          "name": "MDT-AP-2514"
        },
        {
          "name": "MDT-AP-2532"
        },
        {
          "name": "MDT-AP-2562"
        },
        {
          "name": "MDT-AP-2673"
        },
        {
          "name": "MDT-AP-2814"
        },
        {
          "name": "MDT-AP-3017"
        },
        {
          "name": "MDT-AP-3019"
        },
        {
          "name": "MDT-AP-3020"
        },
        {
          "name": "MDT-AP-3401"
        },
        {
          "name": "SJMB014_D"
        },
        {
          "name": "SJMB016_D"
        },
        {
          "name": "SJMB019_D"
        },
        {
          "name": "SJMB024_D"
        },
        {
          "name": "SJMB026_D"
        },
        {
          "name": "SJMB027_D"
        },
        {
          "name": "SJMB032_D"
        },
        {
          "name": "SJMB034_D"
        },
        {
          "name": "SJMB036_D"
        },
        {
          "name": "SJMB037_D"
        },
        {
          "name": "SJMB038_D"
        }
      ]
    }
  ],
  "genegroup": [
    {
      "name": "SHH Signaling",
      "lst": [
        {
          "name": "PTCH1",
          "sortorder": 0
        },
        {
          "name": "SUFU",
          "sortorder": 1
        }
      ]
    },
    {
      "name": "WNT Signaling",
      "lst": [
        {
          "name": "CTNNB1",
          "sortorder": 2
        },
        {
          "name": "APC",
          "sortorder": 3
        }
      ]
    },
    {
      "name": "Cell Cycle",
      "lst": [
        {
          "name": "TP53",
          "sortorder": 4
        }
      ]
    },
    {
      "name": "Transcription Regulation",
      "lst": [
        {
          "name": "GFI1B",
          "sortorder": 5
        }
      ]
    },
    {
      "name": "Epigenetic",
      "lst": [
        {
          "name": "KMT2D",
          "sortorder": 6
        },
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      "Age": "adult",
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    },
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      "Age": "adult",
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    },
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      "Age": "adult",
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    },
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      "Age": "adult",
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    },
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      "Age": "adult",
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    },
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      "Age": "adult",
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      "Age": "adult",
      "Ploidy": "diploid",
      "Gender": "m"
    },
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      "Age": "adult",
      "Ploidy": "diploid",
      "Gender": "m"
    },
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      "Age": "infant",
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      "Gender": "f"
    },
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      "Age": "adult",
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      "Age": "adult",
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    },
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      "Age": "infant",
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    },
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      "Age": "adult",
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    },
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      "Age": "child",
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    },
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      "Age": "adult",
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      "Age": "infant",
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    },
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      "Age": "child",
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    },
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    },
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      "Age": "child",
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    },
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      "Age": "child",
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    },
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    },
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      "Age": "child",
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      "Gender": "m"
    },
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      "Age": "child",
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    },
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      "Age": "adult",
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    },
    "ICGC_LFS_MB2": {
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      "Age": "child",
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      "Gender": "m"
    },
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    },
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      "Age": "infant",
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      "Age": "adult",
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    },
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      "Age": "infant",
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    },
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      "Age": "adult",
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    },
    "MDT-AP-2111": {
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      "Age": "adult",
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    },
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      "Age": "adult",
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    },
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      "Age": "adult",
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    },
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      "Age": "na",
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      "Gender": "t"
    },
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      "Age": "na",
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      "Gender": "f"
    },
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      "Age": "infant",
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    },
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      "Gender": "f"
    },
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      "Age": "infant",
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      "Age": "child",
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    },
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      "Age": "infant",
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    },
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      "Age": "child",
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    },
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      "Age": "na",
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    },
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      "Age": "infant",
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      "Age": "infant",
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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    },
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      "Age": "child",
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    },
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    },
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    },
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      "Gender": "m"
    },
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      "Age": "child",
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    },
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      "Age": "child",
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      "Gender": "f"
    },
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    },
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    },
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      "Age": "child",
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    },
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      "Gender": "f"
    },
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      "Age": "child",
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    },
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      "Age": "child",
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      "Gender": "m"
    },
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      "Age": "child",
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    },
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      "Age": "adult",
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    },
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      "Age": "child",
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    },
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      "Age": "infant",
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    },
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    },
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    },
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      "Age": "child",
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      "Gender": "f"
    },
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    },
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      "Age": "child",
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    },
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    },
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      "Age": "child",
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    },
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      "Age": "child",
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    },
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      "Age": "child",
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    },
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      "Age": "infant",
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    },
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      "Age": "infant",
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    },
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      "Age": "child",
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    },
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    },
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    },
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    },
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      "Age": "child",
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    },
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      "Age": "child",
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    },
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      "Age": "infant",
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    },
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      "Age": "infant",
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      "Gender": "k"
    },
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      "Age": "child",
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    },
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      "Ploidy": "hyperploid",
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    },
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      "Age": "na",
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    },
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    },
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    },
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    },
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    },
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    },
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      "Gender": "na"
    },
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    },
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    },
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    },
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      "Age": "adult",
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    },
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    },
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    },
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The whole-genome landscape of medulloblastoma subtypes

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