Displaying a heatmap showing genomic data for DUX4/ERG ALL cases (columns); genes (rows) are grouped by functional pathway. The color for each type of genetic alteration is defined as per legend. The genomic profiling performed and presence/absence of ERGalt, ALE (Antisense long non-coding RNA associated with ERG) and DUX4 rearrangement are shown at the top: yellow, assay performed or alteration present; white, assay not performed or alteration absent; dark grey, data not available. WGS, whole-genome sequencing; RNA, RNA-seq analysis; WES, whole-exome sequencing. Visualization representative of Zhang et al. 2016, Fig. 3. Mousing over each instance of a mutation provides further information (sample, mutation type, amino acid change, and gene name). Clicking on each gene symbol opens a ProteinPaint view of mutations found within the gene for this cohort. Numbers next to each gene symbol in parentheses indicate the number of samples altered.