Pan-cancer genome and transcriptome analyses of pediatric leukaemias and solid tumours

NCI TARGET

NCI TARGET

Feb 28, 2018

11.7K

Whole Genome Sequencing
Whole Exome Sequencing
RNA Sequencing

Heatmap of genomic mutation data for multiple pediatric leukemias and solid tumors. Here samples (columns) are grouped by cancer subtype; genes (rows) harboring mutations are grouped by functional class. The color for each type of genetic alteration is defined. Mousing over each instance of a mutation provides further information (sample, mutation type, amino acid change, and gene name). Clicking on each gene symbol opens a GenomePaint view of mutations found within the gene across samples in this cohort Numbers in parentheses next to each gene symbol indicate the number of samples altered.

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