Cancer Survivorship Community
The Cancer Survivorship Community shares high quality genomic, clinical, and patient-reported data from survivors of pediatric cancer. To accelerate the rate of discovery in survivorship research we have developed this SJLIFE Survivorship Portal, a data-sharing platform for genomic and clinical data from the St. Jude Lifetime Cohort hosted on the St. Jude Cloud. The Portal features the Clinical Data Browser, GenomePaint, a genetic variant browser, for browsing, visualizing and analyzing clinical and genetic data integratively. Additionally, the Survivorship Portal will serve as a site for an expanding portfolio of risk-prediction tools developed using the SJLIFE cohort, including the recently developed Cumulative Burden Risk-Prediction Tool.
Reference: Epigenetic Age Acceleration and Chronic Health Conditions among Adult Survivors of Childhood Cancer. JNCI 2021
Prediabetes and associated risk of cardiovascular events and chronic kidney disease among adult survivors of childhood cancer in the St. Jude Lifetime Cohort
Dixon SB, Wang F, Lu L, Wilson CL, Jefferies JL, Green DM, Merchant TE, Howell RM, Srivastava DK, Delaney A, Robison LL, Ness KK, Hudson MM, Chemaitilly W, Armstrong GT
Evolving therapies, neurocognitive outcomes and functional independence in adult survivors of childhood glioma
Chiara Papini, PhD, MPH, Sedigheh Mirzaei S., PhD, Mengqi Xing, MR, Ingrid Tonning Olsson, PhD, Peter M K de Blank, MD, MSCE, Katharine R Lange, MD, Ralph Salloum, MD, Deokumar Srivastava, PhD, Wendy M Leisenring, ScD, Rebecca M Howell, PhD, Kevin C Oeffinger, MD, Leslie L Robison, PhD, Gregory T Armstrong, MD, MSCE, Kevin R Krull, PhD, Tara M Brinkman, PhD
Refining the genetic risk of breast cancer with rare haplotypes and pattern mining.
William Letsou, Fan Wang, Wonjong Moon, Cindy Im, Yadav Sapkota, Leslie L Robison, Yutaka Yasui
Cardiac substructure radiation dose and risk of late cardiac disease: A report from the Childhood Cancer Survivor Study.
Bates JE, Shrestha S, Liu Q, Smith SA, Mulrooney DA, Leisenring W, Gibson T, Robison LL, Chow EJ, Oeffinger KC, Armstrong GT, Constine LS, Hoppe BS, Lee C, Yasui Y, Howell RM.
Social cognition and adjustment in adult survivors of pediatric central nervous system tumors
Papini C, Willard VW, Gajjar A, Merchant TE, Srivastava DK, Armstrong GT, Hudson MM, Krull KR, Brinkman TM.
Response-shift effects in childhood cancer survivors: A prospective study
I-Chan Huang, Jin-Ah Sim, DeoKumar Srivastava, Kevin R Krull, Kirsten K Ness, Leslie L Robison, Justin N Baker, Melissa M Hudson, Carolyn E Schwartz
The association of neighborhood characteristics and frailty in childhood cancer survivors: A report from the St. Jude Lifetime Cohort Study
Schwartz LF, Dhaduk R, Howell CR, Brinkman TM, Ehrhardt MJ, Delaney A, Srivastava, Lanctot JQ, Armstrong GT, Robison LL, Hudson MM, Ness KK, Henderson TO.
Cancer-Related Worry as a Predictor of 5-Year Physical Activity Level in Childhood Cancer Survivors
Ware M, Krull KR, Brinkman TM, Armstrong GT, Wilson CL, Mulrooney DA, Wang Z, Lanctot JQ, Partin RE, Shelton K, Hudson MM, Robison LL, Ness KK.
Dynamics of age- versus therapy-related clonal hematopoiesis in long-term survivors of pediatric cancer
Hagiwara K, Natarajan S, Wang Z, Zubair H, Mulder HL, Plyler E, Thimmaiah P, Dong L, Ma X, Ness KK, Li Z, Mulrooney DA, Wilson CL, Yasui Y, Hudson MM, Easton J, Robison LL, Zhang J.
Determinants of health-related quality-of-life in adult survivors of childhood cancer: Integrating personal and societal values through a health utility approach.
Horan M, Srivastava DK, Bhakta N, Ehrhardt MJ, Brinkman TM, Baker J, Yasui Y, Krull KR, Ness KK, Robison LL, Hudson MM, Huang IC.
Health Behavior Profiles in Young Survivors of Childhood Cancer: Findings from the St. Jude Lifetime Cohort Study (SJLIFE)
Webster RT, Dhaduk R, Gordon ML, Partin RE, Kunin-Batson AS, Brinkman TM, Willard VW, Allen JM, Alberts NM, Lanctot JQ, Ehrhardt MJ, Li Z, Hudson MM, Robison LL, Ness KK
The Genetic and Epigenetic Features of Bilateral Wilms Tumor Predisposition: A Report from the Children's Oncology Group AREN18B5-Q Study.
Murphy AJ, Cheng C, Williams J, Shaw TI, Pinto EM, Dieseldorff-Jones K, Brzezinski J, Renfro LA, Tornwall B, Huff V, Hong AL, Mullen EA, Crompton B, Dome JS, Fernandez CV, Geller JI, Ehrlich PF, Mulder H, Oak N, Maciezsek J, Jablonowski C, Fleming AM, Pichavaram P, Morton CL, Easton J, Nichols KE, Clay MR, Santiago T, Zhang J, Yang J, Zambetti GP, Wang Z, Davidoff AM, Chen X.
Distinct DNA methylation signatures associated with blood lipids as exposures or outcomes among survivors of childhood cancer: A Report from the St. Jude Lifetime Cohort
Dong Q, Chen C, Song N, Qin N, Plonski NM, Finch ER, Shelton K, Easton J, Mulder H, Plyer E, Neale G, Walker E, Li Q, Huang IC, Zhang J, Wang H, Hudson MM, Robison LL, Ness KK, Wang Z.
Factors for poor oral health in long-term childhood cancer survivors
Patni T, Lee CT, Li Y, Kaste S, Zhu L, Sun R, Hudson MM, Ness KK, Neumann A, Robison LL.
Social-epigenetic mediators for racial disparities in pulmonary impairment among childhood cancer survivors
Song N, Dong Q, Chen C, Li Q, Mulder H, Plyler E, Easton J, Walker E, Olson S, Neale G, Krull KR, Srivastava DK, Ness KK, Zhang J, Hudson MM, Robison LL, Huang IC, Wang Z.
Epigenetic Age Acceleration and Chronic Health Conditions Among Adult Survivors of Childhood Cancer
Na Qin, Zhenghong Li, Nan Song, Carmen L Wilson, John Easton, Heather Mulder, Emily Plyler, Geoffrey Neale, Emily Walker, Xin Zhou, Haitao Pan 5, Melissa M Hudson, Yutaka Yasui, Leslie L Robison, Jinghui Zhang, Kirsten K Ness, Zhaoming Wang
The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE).
Bhakta N, Liu Q, Ness KK, Baassiri M, Eissa H, Yeo F, Chemaitilly W, Ehrhardt MJ, Bass J, Bishop MW, Shelton K, Lu L, Huang S, Li Z, Caron E, Lanctot J, Howell C, Folse T, Joshi V, Green DM, Mulrooney DA, Armstrong GT, Krull KR, Brinkman TM, Khan RB, Srivastava DK, Hudson MM, Yasui Y, Robison LL
Approach for Classification and Severity Grading of Long-term and Late-Onset Health Events among Childhood Cancer Survivors in the St. Jude Lifetime Cohort
Hudson MM, Ehrhardt MJ, Bhakta N, Baassiri M, Eissa H, Chemaitilly W, Green DM, Mulrooney DA, Armstrong GT, Brinkman TM, Klosky JL, Krull KR, Sabin ND, Wilson CL, Huang IC, Bass JK, Hale K, Kaste S, Khan RB, Srivastava DK, Yasui Y, Joshi VM, Srinivasan S, Stokes D, Hoehn ME, Wilson M, Ness KK, Robison LL
Prospective medical assessment of adults surviving childhood cancer: study design, cohort characteristics, and feasibility of the St. Jude Lifetime Cohort study.
Hudson MM, Ness KK, Nolan VG, Armstrong GT, Green DM, Morris EB, Spunt SL, Metzger ML, Krull KR, Klosky JL, Srivastava DK, Robison LL