Cancer Survivorship Community
The Cancer Survivorship Community shares high quality genomic, clinical, and patient-reported data from survivors of pediatric cancer. To accelerate the rate of discovery in survivorship research we have developed this SJLIFE Survivorship Portal, a data-sharing platform for genomic and clinical data from the St. Jude Lifetime Cohort hosted on the St. Jude Cloud. The Portal features the Clinical Data Browser, GenomePaint, a genetic variant browser, for browsing, visualizing and analyzing clinical and genetic data integratively. Additionally, the Survivorship Portal will serve as a site for an expanding portfolio of risk-prediction tools developed using the SJLIFE cohort, including the recently developed Cumulative Burden Risk-Prediction Tool.
Reference: Epigenetic Age Acceleration and Chronic Health Conditions among Adult Survivors of Childhood Cancer. JNCI 2021
Late subsequent leukemia after childhood cancer: A report from the Childhood Cancer Survivor Study (CCSS).
Ghosh T, Hyun G, Conces M, Arnold MA, Howell RM, Henderson TO, McDonald A, Robison LL, Yasui Y, Ness KK, Armstrong GT, Neglia JP, Turcotte LM.
Exercise and Quality Diet after Leukemia: A Randomized Weight Loss Trial among Adult Survivors of Childhood Leukemia in the Childhood Cancer Survivor Study
Friedman DN, Chou JF, Clark JM, Moskowitz CS, Ford JS, Armstrong GT, Mubdi N, McDonald A, Nathan PC, Sklar CA, Ramanathan L, Robison LL, Oeffinger KC, Tonorezos ES
Long-term outcomes among survivors of childhood osteosarcoma: A report from the Childhood Cancer Survivor Study (CCSS).
Becktell K, Chen Y, Yasui Y, Phelan R, Armstrong GT, Link M, Oeffinger K, Snyder C, Daw N, Weil B, Weldon C, Chow E, Schwartz CL.
Neurocognitive outcomes and functional independence in adult survivors of childhood medulloblastoma diagnosed over three decades
Papini C, Mirzaei S S, Xing M, Tonning Olsson I, Sollum R, de Blank PMK, Lange KR, King TZ, Srivastava DK, Leisenring WM, Howell RM, Oeffinger KC, Robison LL, Armstrong GT, Krull KR, Brinkman TM
Using neurocognitive phenotypes to inform interventions for adult survivors of childhood cancer
Banerjee P, Phillips NS, Liu W, Ehrhardt MJ, Bhakta N, Brinkman TM, Williams ALM, Yasui Y, Khan RB, Srivastava DK, Ness KK, Robison LL, Hudson MM, Krull KR
Estimation of personal symptom networks using the Ising Model for adult survivors of childhood cancer: A simulation study with real-world data application
Zhou Y, Horan MR, Deshpande S, Ness KK, Hudson MM, Huang I-C, Srivastava DK.
The burden of cardiovascular disease and risk for subsequent major adverse cardiovascular events in survivors of childhood cancer: a prospective, longitudinal analysis from the St Jude Lifetime Cohort Study
Hammoud RA, Liu Q, Dixon SB, Onerup A, Mulrooney DA, Huang IC, Jefferies JL, Rhea IB, Ness KK, Ehrhardt MJ, Hudson MM, Ky B, Bhakta N, Sapkota Y, Yasui Y, Armstrong GT
Adverse childhood experiences, resilience, and cardiovascular disease in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study
Schwartz LF, Stratton KL, Leisenring WM, Marron Rodriguez S, Alston S, McDonald A, Vukadinovich C, Rinehardt D, Oeffinger KC, Chow EJ, Krull KR, Brinkman TM, Nathan PC, Tan MM, McCrae JS, Burkhardt T, Ness KK, Armstrong GT, Henderson TO.
Associations between personality type and longitudinal change in exercise intervention outcomes in survivors of childhood cancer
Ware ME, Goodenough CG, Wogksch MD, Neel M, Partin RE, Lanctot JQ, Mulrooney DA, Hudson MM, Ness KK
Multilevel characteristics of cumulative symptom burden in young survivors of childhood cancer.
"Horan MR, Srivastava DK, Choi J, Krull KR, Armstrong GT, Ness KK, Hudson MM, Baker JN, Huang IC "
St. Jude Survivorship Portal: sharing and analyzing large clinical and genomic datasets from pediatric cancer survivors
Gavriel Y. Matt, Edgar Sioson, Kyla Shelton, Jian Wang, Congyu Lu, Airen Zaldivar Peraza, Karishma Gangwani, Robin Paul, Colleen Reilly, Aleksandar Acić, Qi Liu, Stephanie R. Sandor, Clay McLeod, Jaimin Patel, Fan Wang, Cindy Im, Zhaoming Wang, Yadav Sapkota, Carmen L. Wilson, Nickhill Bhakta, Kirsten K. Ness, Gregory T. Armstrong, Melissa M. Hudson, Leslie L. Robison, Jinghui Zhang, Yutaka Yasui, Xin Zhou
Feasibility of remote monitoring for fatal coronary heart disease using Apple Watch ECGs
Butler L, Ivanov A, Celik T, Karabayir I, Chinthala L, Hudson MM, Ness KK, Mulrooney DA, Dixon SB, Tootooni M, Doerr A, Jaeger B, Davis RL, McManus DD, Herrington D, Akbilgic O
Associations of Seven Measures of Biological Age Acceleration with Frailty and All-Cause Mortality Among Adult Survivors of Childhood Cancer in the St. Jude Lifetime Cohort
Guida JL, Hyun G, Belsky DW, Armstrong GT, Ehrhardt MJ, Hudson MM, Green PA, Robison LL, Streck BP, Tonorezos ES, Yasui Y, Wilson CL, Wang Z, Ness KK
Autonomic dysfunction among adult survivors of childhood cancer in the St. Jude Lifetime Cohort Study.
Groarke JD, Ness KK, Dhaduk R, Plana JC, Durand JB, Luepker RV, Joshi VM, Ehrhardt M, Mulrooney DA, Dixon SB, Nohria A, Green DM, Howell RM, Srivastava DK, Jefferies JL, Robison LL, Hudson MM, Armstrong GT.
Machine learning to optimize automated RH genotyping using whole-exome sequencing data
Chang TC, Yu J, Wang Z, Hankins JS, Weiss MJ, Wu G, Westhoff CM, Chou ST, Zheng Y
Hypogonadism and neurocognitive outcomes among childhood cancer survivors
Yoshida T, Alexander T, Xing M, Williams ALM, Lubas M, Brinkman TM, Chemaitilly W, Robison LL, Hudson MM, Krull KR, Delaney A.
Polygenic risk scores, radiation treatment exposures and subsequent cancer risk in childhood cancer survivors.
Gibson TM, Karyadi DM, Hartley SW, Arnold MA, de Gonzalez AB, Conces MR, Howell RM, Kapoor V, Leisenring WM, Neglia JP, Sampson JN, Turcotte LM, Chanock SJ, Armstrong GT, Morton LM
Health-related quality of life and DNA methylation-based aging biomarkers among survivors of childhood cancer
Plonski NM, Pan Y, Chen C, Dong Q, Zhang X, Song N, Shelton K, Easton J, Mulder H, Zhang J, Neale G, Walker E, Wang H, Webster R, Brinkman T, Krull KR, Armstrong GT, Ness KK, Hudson MM, Li Q, Huang IC, Wang Z.
Severe sepsis during treatment for childhood leukemia and sequelae among adult survivors
Goggin KP, Lu L, Lee DE, Howell CR, Srivastava DK, Brinkman TM, Armstrong GT, Bhakta N, Robison LL, Ehrhardt MJ, Hudson MM, Krull KR, Pui CH, Rubnitz J, Ness KK, Wolf J
Temporal changes in treatment and late mortality and morbidity in adult survivors of childhood glioma: A report from the Childhood Cancer Survivor Study
de Blank PMK, Lange KR, Xing M, Mirzaei Salehabadi S, Srivastava D, Brinkman TM, Ness KK, Oeffinger KC, Neglia J, Krull KR, Nathan PC, Howell R, Turcotte LM, Leisenring W, Armstrong GT, Okcu MF, Bowers DC
Systemic biological mechanisms of neurocognitive dysfunction in long-term survivors of childhood Hodgkin lymphoma.
Williams ALM, Liu W, Ehrhardt MJ, Mirzaei Salehabadi S, Panoskaltsis-Mortari A, Phillips NS, Mulrooney DA, Flerlage JE, Yasui Y, Srivastava DK, Robison LL, Hudson MM, Ness KK, Sabin ND, Krull KR.
Risk factors for neurocognitive impairment, emotional distress and poor quality of life in survivors of pediatric rhabdomyosarcoma: A report from the Childhood Cancer Survivor Study.
van der Plas E, Darji H, Srivastava K, Schapiro M, Jeffe D, Perkins S, Howell R, Leisenring W, Armstrong GT, Oeffinger K, Krull K, Edelstein K, Hayashi RJ.
Mechanisms of sleep disturbances in long-term cancer survivors: a childhood cancer survivor study report
Daniel LC, Wang H, Brinkman TM, Ruble K, Zhou ES, Palesh O, Stremler R, Howell R, Mulrooney DA, Crabtree VM, Mostoufi-Moab S, Oeffinger K, Neglia J, Yasui Y, Armstrong GT, Krull K
Lifestyle and subsequent malignant neoplasms in childhood cancer survivors: A report from the St. Jude Lifetime Cohort Study.
Onerup A, Bhatia S, Mirzaei Salehabadi S, Ware M, Yasui Y, Joffe L, Turcotte L, Goodenough C, Sapkota Y, Wogksch M, Ehrhardt M, Armstrong GT, Hudson MM, Ness KK.
Movement efficiency in survivors of childhood Acute Lymphoblastic leukemia: A report from the St. Jude Lifetime Cohort Study.
Onerup A, Mirzaei S, Wogksch MD, Goodenough CG, Lambert G, Sapkota Y, Mulrooney DA, Hudson MM, Jacola LM, Ness KK.