Cancer Survivorship Community
The Cancer Survivorship Community shares high quality genomic, clinical, and patient-reported data from survivors of pediatric cancer. To accelerate the rate of discovery in survivorship research we have developed this SJLIFE Survivorship Portal, a data-sharing platform for genomic and clinical data from the St. Jude Lifetime Cohort hosted on the St. Jude Cloud. The Portal features the Clinical Data Browser, GenomePaint, a genetic variant browser, for browsing, visualizing and analyzing clinical and genetic data integratively. Additionally, the Survivorship Portal will serve as a site for an expanding portfolio of risk-prediction tools developed using the SJLIFE cohort, including the recently developed Cumulative Burden Risk-Prediction Tool.
Reference: Epigenetic Age Acceleration and Chronic Health Conditions among Adult Survivors of Childhood Cancer. JNCI 2021
Polygenic risk scores, radiation treatment exposures and subsequent cancer risk in childhood cancer survivors.
Gibson TM, Karyadi DM, Hartley SW, Arnold MA, de Gonzalez AB, Conces MR, Howell RM, Kapoor V, Leisenring WM, Neglia JP, Sampson JN, Turcotte LM, Chanock SJ, Armstrong GT, Morton LM.
Sexual dysfunction among long-term survivors of Hodgkin lymphoma.
Hanzlik E, Sabin ND, Yoshida T, Delaney A, Xie L, Darji H, Srivastava D, Mulrooney DA, Hudson MM, Krull KR, Khan RB.
Motor and sensory impairment in survivors of childhood central nervous system (CNS) tumors in the St. Jude Lifetime Cohort (SJLIFE)
Rodwin RL, Wang F, Lu L, Li Z, Srivastava DK, Phillips NS, Khan RB, Brinkman TM, Krull KR, Boop FA, Armstrong GT, Merchant TE, Gajjar A, Robison LL, Hudson MM, Kadan-Lottick NS, Ness KK
Plant-based, fast-food, Western-contemporary, and animal-based dietary patterns and risk of premature aging in adult survivors of childhood cancer: a cross-sectional study
Lan T, Wang M, Williams AM, Ehrhardt MJ, Lanctot JQ, Jiang S, Krull KR, Armstrong GT, Hudson MM, Colditz GA, Robison LL, Ness KK, Park Y
Temporal trends of subsequent CNS malignancies among survivors of childhood cancer.
Galvin RT, Chen Y, Yuan Y, Cooney T, Howell R, Smith S, Arnold MA, Conces M, Leisenring W, Armstrong GT, Neglia JP, Turcotte LM.
The accuracy of estimating equations for the evaluation of kidney function in adult survivors of unilateral, nonmetastatic, non-syndromic Wilms tumor: A pilot study from the St. Jude Lifetime Cohort Study
Green DM, Wang M, Krasin MJ, Davidoff AM, Srivastava D, Jay DW, Ness KK, Shulkin BL, Lanctot JQ, Shelton KC, Brennan RC, Mulrooney DA, Ehrhardt MJ, Dixon SB, Kurt BA, Robison LL, Hudson MM, Spunt SL
Characterization of Patient Activation Among Childhood Cancer Survivors in the St. Jude Lifetime Cohort (SJLIFE)
Ware ME, de la Cruz A, Dong Q, Shelton K, Brinkman TM, Huang I-C, Webster R, Potter B, Krull K, Mirzaei S, Ehrhardt MJ, Hudson MM, Armstrong GT, Ness K
Neighborhood Vulnerability and Associations with Poor Health-Related Quality-of-Life Among Adult Survivors of Childhood Cancer
Jaesung Choi, Madeline R. Horan, Tara M. Brinkman, D. Kumar Srivastava, Kirsten K. Ness, Gregory T. Armstrong, Melissa M. Hudson, I-Chan Huang
Joint imbalance adaptation for radiology report generation
Wu Y, Huang IC, Huang X.
Keratinocyte carcinomas in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study
Boull C, Chen Y, Im C, Geller A, Sapkota Y, Bates JE, Howell R, Arnold MA, Conces M, Constine LS, Robison L, Yasui Y, Armstrong GT, Neglia JP, Turcotte LM
Associations between perceived cancer impact and measures of health behavior in survivors of childhood cancer
Ware ME, Goodenough CG, Wogksch MD, Krull KR, Brinkman TM, Hebert JR, Willard V, Webster R, Ehrhardt M, Mirzaei S, Armstrong GT, Hudson MM, Ness KK
Sugar and sugar-sweetened beverages in relation to premature aging in adult survivors of childhood cancer
Lan T, Wang M, Williams ALM, Ehrhardt MJ, Jiang S, Huang I-C, Lanctot JQ, Krull KR, Armstrong GT, Hudson MM, Colditz GA, Robison LL, Ness KK, Park Y
Exercise and Quality Diet after Leukemia: A Randomized Weight Loss Trial among Adult Survivors of Childhood Leukemia in the Childhood Cancer Survivor Study
Friedman DN, Chou JF, Clark JM, Moskowitz CS, Ford JS, Armstrong GT, Mubdi N, McDonald A, Nathan PC, Sklar CA, Ramanathan L, Robison LL, Oeffinger KC, Tonorezos ES
Late subsequent leukemia after childhood cancer: A report from the Childhood Cancer Survivor Study (CCSS).
Ghosh T, Hyun G, Conces M, Arnold MA, Howell RM, Henderson TO, McDonald A, Robison LL, Yasui Y, Ness KK, Armstrong GT, Neglia JP, Turcotte LM.
Long-term outcomes among survivors of childhood osteosarcoma: A report from the Childhood Cancer Survivor Study (CCSS).
Becktell K, Chen Y, Yasui Y, Phelan R, Armstrong GT, Link M, Oeffinger K, Snyder C, Daw N, Weil B, Weldon C, Chow E, Schwartz CL.
Neurocognitive outcomes and functional independence in adult survivors of childhood medulloblastoma diagnosed over three decades
Papini C, Mirzaei S S, Xing M, Tonning Olsson I, Sollum R, de Blank PMK, Lange KR, King TZ, Srivastava DK, Leisenring WM, Howell RM, Oeffinger KC, Robison LL, Armstrong GT, Krull KR, Brinkman TM
Using neurocognitive phenotypes to inform interventions for adult survivors of childhood cancer
Banerjee P, Phillips NS, Liu W, Ehrhardt MJ, Bhakta N, Brinkman TM, Williams ALM, Yasui Y, Khan RB, Srivastava DK, Ness KK, Robison LL, Hudson MM, Krull KR
Estimation of personal symptom networks using the Ising Model for adult survivors of childhood cancer: A simulation study with real-world data application
Zhou Y, Horan MR, Deshpande S, Ness KK, Hudson MM, Huang I-C, Srivastava DK.
The burden of cardiovascular disease and risk for subsequent major adverse cardiovascular events in survivors of childhood cancer: a prospective, longitudinal analysis from the St Jude Lifetime Cohort Study
Hammoud RA, Liu Q, Dixon SB, Onerup A, Mulrooney DA, Huang IC, Jefferies JL, Rhea IB, Ness KK, Ehrhardt MJ, Hudson MM, Ky B, Bhakta N, Sapkota Y, Yasui Y, Armstrong GT
Multilevel characteristics of cumulative symptom burden in young survivors of childhood cancer.
"Horan MR, Srivastava DK, Choi J, Krull KR, Armstrong GT, Ness KK, Hudson MM, Baker JN, Huang IC "
St. Jude Survivorship Portal: sharing and analyzing large clinical and genomic datasets from pediatric cancer survivors
Gavriel Y. Matt, Edgar Sioson, Kyla Shelton, Jian Wang, Congyu Lu, Airen Zaldivar Peraza, Karishma Gangwani, Robin Paul, Colleen Reilly, Aleksandar Acić, Qi Liu, Stephanie R. Sandor, Clay McLeod, Jaimin Patel, Fan Wang, Cindy Im, Zhaoming Wang, Yadav Sapkota, Carmen L. Wilson, Nickhill Bhakta, Kirsten K. Ness, Gregory T. Armstrong, Melissa M. Hudson, Leslie L. Robison, Jinghui Zhang, Yutaka Yasui, Xin Zhou
Autonomic dysfunction among adult survivors of childhood cancer in the St. Jude Lifetime Cohort Study.
Groarke JD, Ness KK, Dhaduk R, Plana JC, Durand JB, Luepker RV, Joshi VM, Ehrhardt M, Mulrooney DA, Dixon SB, Nohria A, Green DM, Howell RM, Srivastava DK, Jefferies JL, Robison LL, Hudson MM, Armstrong GT.
Hypogonadism and neurocognitive outcomes among childhood cancer survivors
Yoshida T, Alexander T, Xing M, Williams ALM, Lubas M, Brinkman TM, Chemaitilly W, Robison LL, Hudson MM, Krull KR, Delaney A.
Machine learning to optimize automated RH genotyping using whole-exome sequencing data
Chang TC, Yu J, Wang Z, Hankins JS, Weiss MJ, Wu G, Westhoff CM, Chou ST, Zheng Y
Health-related quality of life and DNA methylation-based aging biomarkers among survivors of childhood cancer
Plonski NM, Pan Y, Chen C, Dong Q, Zhang X, Song N, Shelton K, Easton J, Mulder H, Zhang J, Neale G, Walker E, Wang H, Webster R, Brinkman T, Krull KR, Armstrong GT, Ness KK, Hudson MM, Li Q, Huang IC, Wang Z.