Cancer Survivorship Community
The Cancer Survivorship Community shares high quality genomic, clinical, and patient-reported data from survivors of pediatric cancer. To accelerate the rate of discovery in survivorship research we have developed this SJLIFE Survivorship Portal, a data-sharing platform for genomic and clinical data from the St. Jude Lifetime Cohort hosted on the St. Jude Cloud. The Portal features the Clinical Data Browser, GenomePaint, a genetic variant browser, for browsing, visualizing and analyzing clinical and genetic data integratively. Additionally, the Survivorship Portal will serve as a site for an expanding portfolio of risk-prediction tools developed using the SJLIFE cohort, including the recently developed Cumulative Burden Risk-Prediction Tool.
Reference: Epigenetic Age Acceleration and Chronic Health Conditions among Adult Survivors of Childhood Cancer. JNCI 2021
Breast cancer recurrence and mortality among survivors of childhood cancer.
Im C, Hasan H, Srinivasan A, Stene E, McDonald AJ, Moskowitz CS, Henderson TO, Armstrong GT, Yasui Y, Nanda R, Oeffinger KC, Neglia JP, Blaes A, Turcotte LM.
Association of neuropathy, sarcopenia and physical function in acute lymphoblastic leukemia survivors with chemotherapy alone.
Fridh MK, Xing M, Mirzaei S, Mizrahi D, Larsen HB, Dixon SB, Phillips NS, Krull KR, Inaba H, Pui CH, Karol SE, Delaney A, Kaste SC, Hudson MM, Ness KK.
Optimizing prompting strategies improves large language model classification of pain- and fatigue-related functional impact in childhood cancer survivors.
Sim J, Horan MR, Huang X, Kim M, Srivastava DK, Ness KK, Hudson MM, Baker JN, Huang I-C.
Patient-reported symptoms in predicting the subsequent progression of chronic health conditions among childhood cancer survivors.
Horan MR, Liu W, Wang M, Srivastava D, Ehrhardt MJ, Mulrooney DA, Chemaitilly W, Ness KK, Baker JN, Armstrong GT, Hudson MM, Krull KR, Huang IC.
Mortality after colorectal cancer among survivors of childhood cancer
Major A, Chou J, Lam H, Kim KE, Turcotte LM, Leisenring W, Yasui Y, Neglia JP, Curry M, Howell RM, Oeffinger KC, Hodgson D, Nathan PC, Armstrong GT, Moskowitz CS, Henderson TO
Hypothalamic-pituitary deficiency after radiation in childhood cancer survivors is associated with rare variants in TNS2
Yoshida T, Wang F, Moon W, Mostoufi-Moab S, Wang H, Neupane A, Wang J, Sapkota Y, Wilson CL, Mirzaei S, Wang Z, Zhang J, Merchant TE, Armstrong GT, Ness KK, Hudson MM, Yasui Y, Delaney A
Stressful events reported by childhood cancer survivors and community controls from the St. Jude Lifetime (SJLIFE) Cohort: A mixed method study.
Ware ME, Clayton CK, Wang F, Mirzaei S, Shelton K, Brinkman TM, Willard V, Sharp KMH, Krull K, Schwartz LF, Hudson MM, Armstrong GT, Ness KK, Webster RT
Long-term outcomes associated with posterior fossa syndrome in survivors of childhood medulloblastoma.
Sarvode S, Dhaduk R, Chen Y, Taneja S, Bass JK, Partin R, Szymanek K, Wogksch M, Conklin HM, Raches D, Merchant TE, Klimo P, Gajjar A, Krull KR, Khan RB, Armstrong GT, Ness KK, Robinson GW, Mirzaei S, Brinkman TM, Hudson MM, Phillips NS.
Potential of exercise for prevention of cardiovascular disease in survivors of childhood Hodgkin lymphoma.
Onerup A, Liu Q, Izumi S, Martinez-Martinez JM, Dixon SB, Chow EJ, Hudson MM, Snyder C, Nathan PC, Armstrong GT, Ness KK, Yasui Y.
Neurocognitive impairment and financial hardship in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study.
Zheng DJ, Bhatia S, Mirzaei S, Aplenc R, Armstrong GT, Bona K, Brinkman TM, Brouwers P, Edelstein K, Getz K, Huang IC, Kirchhoff AC, Mostoufi-Moab S, Park ER, Snyder C, Yabroff KR, Yasui Y, Krull K, Nathan PC
Epigenome-wide analysis identifies DNA methylation mediators of treatment-related cardiometabolic risk in survivors of childhood cancer.
Eulalio T, Kim Y, Meng X, Plonski NM, Shelton K, Mulder H, Plyer E, Easton J, Chen X, Zhang J, Walker E, Neale G, Ni M, Lucas JT, Chatterjee N, Wang ZQ, Srivastava K, Ky B, Dixon SB, Ness KK, Hudson MM, Armstrong GT, Wang Z.
Discovery of genetic susceptibility variants in pediatric and adult ependymoma
Strauss JD, Shetty PB, Tsavachidis S, Byun J, Mack SC, Xiangjun X, Armstrong TS, Gilbert MR; (on behalf of NCI-CONNECT); Mirabello L, Bhatia S, Leisenring WM, Morton LM, Armstrong GT, Foss-Skiftesvik J, Hagen CM, Bybjerg-Grauholm J; iPSYCH Consortium; Ghozal M, Bonaventure A, Clavel J, Bondy ML; (on behalf of GICC); Amos CI, Hoang TT, Scheurer ME
Paired clinical 12 lead and Apple watch electrocardiogram data repository from childhood cancer survivors authors.
Akbilgic O, Karabayir I, Patterson L, Dixon SB, Mulrooney DA, Ness KK, Hudson MM.
Accelerated Brain Aging, Atherogenicity, and Neurocognition in Adult Survivors of Childhood Cancer.
Phillips NS, Zhang S, Baedke J, Ji Q, Sabin ND, Ness KK, Hudson MM, Yasui Y, Mahapatra S, Kumbaji M, Tatevossian RG, Scoggins MA, Williams AM, Krull KR.
Symptom burden, healthcare utilization, and risky behaviors in survivors of the Childhood Cancer Survivor Study (CCSS): An observation cohort study
Webster R, Srivastava DK, Xie L, Darji H, Liu W, McGrady ME, Brinkman TM, Alberts NM, Ness KK, Fuemmeler B, Kunin-Batson AS, Huang IC, Armstrong GT, Howell RM, Green DM, Yasui Y, Krull KR
Late morbidity and mortality in survivors of childhood ependymoma: A report from the Childhood Cancer Survivor Study (CCSS)
Lange KR, de Blank P, Xing M, Mirzaei S, Srivastava DK, Oeffinger K, Neglia J, Krull K, Nathan PC, Howell R, Ness KK, Turcotte LM, Leisenring W, Armstrong GT, Brinkman T, Bowers DC, Okcu MF
Epigenetic age acceleration, telomere length, and neurocognitive function in long-term survivors of childhood cancer: A report from the St. Jude Lifetime Cohort
Williams AM, Phillips NS, Dong Q, Ehrhardt MJ, Gilmore G, Loh KP, Meng X, Ness KK, Hudson MM, Robison LL, Wang Z, Krull KR
Psychosocial health and chronic health conditions among bereaved siblings: A report from the Childhood Cancer Survivorship Study (CCSS)
Sharma P, George N, Srivastava D, Chow EJ, Alderfer MA, Leisenring W, Long KA, Lown AE, Oeffinger KC, Zeltzer LK, Armstrong GT, Krull KR, Brinkman TM, Buchbinder D
Estimating personal temporal symptom networks for childhood cancer survivors
Zhou Y, Deshpande S, Horan MR, Choi J, Mulrooney D, Ness KK, Hudson MM, Srivastava D, Huang I-C
Diabetes mellitus and neurocognition: A report from the Childhood Cancer Survivor Study
Webster RT, Mirzaei S, Bhatia S, Srivastava DK, Mostoufi-Moab S, Dixon SB, Chow EJ, Armstrong GT, Krull KR, van der Plas E
Health outcomes beyond age 50 years in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study
Bhandari R, Chen Y, Chow EJ, Howell RM, Kenney LB, Krull KR, Leisenring W, Nathan PC, Neglia JP, Ness KK, Oeffinger KC, Snyder C, Turcotte LM, Wong LF, Yasui Y, Armstrong GT, Armenian SH
Body mass index, physical activity, and subsequent neoplasm risk among survivors of childhood cancer: A report from the Childhood Cancer Survivor Study
Joffe L, Mirzaei S, Bhatia S, Darji H, Ness KK, Onerup A, Ladas EJ, Im C, Lupo PJ, Oeffinger KC, Friedman DN, Howell RM, Conces MR, Arnold MA, Armstrong GT, Neglia JP, Yasui Y, Kadan-Lottick NS, Turcotte LM
Associations between Cardiopulmonary Fitness and Cardiovascular Events in Survivors of Childhood Cancer: A Report from the St. Jude Lifetime Cohort
Wogksch M, Ware M, Onerup A, O'Neil S, Nolan V, Smeltzer M, Mzayek F, Mulrooney DA, Ehrhardt M, Dixon S, Rhea I, Srivastava D, Armstrong GT, Hudson MM, Ness KK
Cardiometabolic outcomes after bariatric surgery in adult survivors of childhood cancer: a SJLIFE report
Berkman AM, Liu Q, Yasui Y, Grishman E, Ehrhardt MJ, Ky B, Rhea IB, Delaney A, Wilson CL, Ware M, Ness KK, Armstrong GT, Hudson MM, Dixon SB
Epigenetic Age Acceleration Mediates Treatment Effects on Cardiometabolic and Cardiovascular Risk in Childhood Cancer Survivors
Meng X, Eulalio T, Kim Y, Easton J, Mulder HL, Walker E, Neale G, Song N, Shelton K, Howell RM, Xing M, S M, Srivastava DK, Ky B, Dixon SB, Hudson MM, Ness KK, Armstrong GT, Wang Z