Cancer Survivorship Community
The Cancer Survivorship Community shares high quality genomic, clinical, and patient-reported data from survivors of pediatric cancer. To accelerate the rate of discovery in survivorship research we have developed this SJLIFE Survivorship Portal, a data-sharing platform for genomic and clinical data from the St. Jude Lifetime Cohort hosted on the St. Jude Cloud. The Portal features the Clinical Data Browser, GenomePaint, a genetic variant browser, for browsing, visualizing and analyzing clinical and genetic data integratively. Additionally, the Survivorship Portal will serve as a site for an expanding portfolio of risk-prediction tools developed using the SJLIFE cohort, including the recently developed Cumulative Burden Risk-Prediction Tool.
Reference: Epigenetic Age Acceleration and Chronic Health Conditions among Adult Survivors of Childhood Cancer. JNCI 2021
Mortality after colorectal cancer among survivors of childhood cancer
Major A, Chou J, Lam H, Kim KE, Turcotte LM, Leisenring W, Yasui Y, Neglia JP, Curry M, Howell RM, Oeffinger KC, Hodgson D, Nathan PC, Armstrong GT, Moskowitz CS, Henderson TO
Hypothalamic-pituitary deficiency after radiation in childhood cancer survivors is associated with rare variants in TNS2
Yoshida T, Wang F, Moon W, Mostoufi-Moab S, Wang H, Neupane A, Wang J, Sapkota Y, Wilson CL, Mirzaei S, Wang Z, Zhang J, Merchant TE, Armstrong GT, Ness KK, Hudson MM, Yasui Y, Delaney A
Stressful events reported by childhood cancer survivors and community controls from the St. Jude Lifetime (SJLIFE) Cohort: A mixed method study.
Ware ME, Clayton CK, Wang F, Mirzaei S, Shelton K, Brinkman TM, Willard V, Sharp KMH, Krull K, Schwartz LF, Hudson MM, Armstrong GT, Ness KK, Webster RT
Neurocognitive impairment and financial hardship in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study.
Zheng DJ, Bhatia S, Mirzaei S, Aplenc R, Armstrong GT, Bona K, Brinkman TM, Brouwers P, Edelstein K, Getz K, Huang IC, Kirchhoff AC, Mostoufi-Moab S, Park ER, Snyder C, Yabroff KR, Yasui Y, Krull K, Nathan PC
Symptom burden, healthcare utilization, and risky behaviors in survivors of the Childhood Cancer Survivor Study (CCSS): An observation cohort study
Webster R, Srivastava DK, Xie L, Darji H, Liu W, McGrady ME, Brinkman TM, Alberts NM, Ness KK, Fuemmeler B, Kunin-Batson AS, Huang IC, Armstrong GT, Howell RM, Green DM, Yasui Y, Krull KR
Late morbidity and mortality in survivors of childhood ependymoma: A report from the Childhood Cancer Survivor Study (CCSS)
Lange KR, de Blank P, Xing M, Mirzaei S, Srivastava DK, Oeffinger K, Neglia J, Krull K, Nathan PC, Howell R, Ness KK, Turcotte LM, Leisenring W, Armstrong GT, Brinkman T, Bowers DC, Okcu MF
Epigenetic age acceleration, telomere length, and neurocognitive function in long-term survivors of childhood cancer: A report from the St. Jude Lifetime Cohort
Williams AM, Phillips NS, Dong Q, Ehrhardt MJ, Gilmore G, Loh KP, Meng X, Ness KK, Hudson MM, Robison LL, Wang Z, Krull KR
Psychosocial health and chronic health conditions among bereaved siblings: A report from the Childhood Cancer Survivorship Study (CCSS)
Sharma P, George N, Srivastava D, Chow EJ, Alderfer MA, Leisenring W, Long KA, Lown AE, Oeffinger KC, Zeltzer LK, Armstrong GT, Krull KR, Brinkman TM, Buchbinder D
Estimating personal temporal symptom networks for childhood cancer survivors
Zhou Y, Deshpande S, Horan MR, Choi J, Mulrooney D, Ness KK, Hudson MM, Srivastava D, Huang I-C
Diabetes mellitus and neurocognition: A report from the Childhood Cancer Survivor Study
Webster RT, Mirzaei S, Bhatia S, Srivastava DK, Mostoufi-Moab S, Dixon SB, Chow EJ, Armstrong GT, Krull KR, van der Plas E
Health outcomes beyond age 50 years in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study
Bhandari R, Chen Y, Chow EJ, Howell RM, Kenney LB, Krull KR, Leisenring W, Nathan PC, Neglia JP, Ness KK, Oeffinger KC, Snyder C, Turcotte LM, Wong LF, Yasui Y, Armstrong GT, Armenian SH
Body mass index, physical activity, and subsequent neoplasm risk among survivors of childhood cancer: A report from the Childhood Cancer Survivor Study
Joffe L, Mirzaei S, Bhatia S, Darji H, Ness KK, Onerup A, Ladas EJ, Im C, Lupo PJ, Oeffinger KC, Friedman DN, Howell RM, Conces MR, Arnold MA, Armstrong GT, Neglia JP, Yasui Y, Kadan-Lottick NS, Turcotte LM
Associations between Cardiopulmonary Fitness and Cardiovascular Events in Survivors of Childhood Cancer: A Report from the St. Jude Lifetime Cohort
Wogksch M, Ware M, Onerup A, O'Neil S, Nolan V, Smeltzer M, Mzayek F, Mulrooney DA, Ehrhardt M, Dixon S, Rhea I, Srivastava D, Armstrong GT, Hudson MM, Ness KK
Cardiometabolic outcomes after bariatric surgery in adult survivors of childhood cancer: a SJLIFE report
Berkman AM, Liu Q, Yasui Y, Grishman E, Ehrhardt MJ, Ky B, Rhea IB, Delaney A, Wilson CL, Ware M, Ness KK, Armstrong GT, Hudson MM, Dixon SB
Epigenetic Age Acceleration Mediates Treatment Effects on Cardiometabolic and Cardiovascular Risk in Childhood Cancer Survivors
Meng X, Eulalio T, Kim Y, Easton J, Mulder HL, Walker E, Neale G, Song N, Shelton K, Howell RM, Xing M, S M, Srivastava DK, Ky B, Dixon SB, Hudson MM, Ness KK, Armstrong GT, Wang Z
Predicting the 10-year risk of cardiomyopathy in long-term survivors of childhood cancer
Petrykey K, Neupane A, Wang H, Dixon SB, Im C, Ehrhardt MJ, Mulrooney DA, Sharafeldin N, Wang X, Howell R, Jefferies JL, Burridge PW, Oeffinger KC, Gramatges MM, Bhatia S, Robison LL, Ness KK, Hudson MM, Chow EJ, Armstrong GT, Yasui Y, Sapkota Y
Perception of infertility risk vs. objective fertility status in males exposed to alkylating agents but not radiation therapy: a report from the St. Jude Lifetime (SJLIFE) cohort study
Ware ME, We RK, Kutteh WH, Webster RT, Delaney A, Yu C, Shelton K, Srivastava D, Taneja S, Sapkota Y, Wang Z, Hudson MM, Lucas J, Armstrong GT, Ness KK, Green DM
Treatment, toxicity, and mortality after subsequent breast cancer in female survivors of childhood cancer
Im C, Hasan H, Stene E, Monick S, Rader R, Sheade J, Wolfe H, Lu Z, Spector LG, McDonald AJ, Nolan V, Arnold MA, Conces MR, Moskowitz CS, Henderson TO, Robison LL, Armstrong GT, Yasui Y, Nanda R, Oeffinger KC, Neglia JP, Blaes A, Turcotte LM
Plant-based, fast-food, Western-contemporary, and animal-based dietary patterns and risk of premature aging in adult survivors of childhood cancer: a cross-sectional study
Lan T, Wang M, Williams AM, Ehrhardt MJ, Lanctot JQ, Jiang S, Krull KR, Armstrong GT, Hudson MM, Colditz GA, Robison LL, Ness KK, Park Y
Frailty and sleep in adult survivors of childhood cancer: A Childhood Cancer Survivor Study report Survivor Study
Daniel LC, Lubas MM, Wang H, Ness KK, Szklo-Coxe M, Williams ALM, Mulrooney DA, Howell R, Leisenring W, Yasui Y, Robison LL, Armstrong GT, Chow EJ, Krull KR, Brinkman TM
Temporal trends of subsequent CNS malignancies among survivors of childhood cancer.
Galvin RT, Chen Y, Yuan Y, Cooney T, Howell R, Smith S, Arnold MA, Conces M, Leisenring W, Armstrong GT, Neglia JP, Turcotte LM.
Kidney function and body composition in adult survivors of unilateral, non-syndromic Wilms tumor: A report from the St. Jude Lifetime Cohort study
Green DM, Li K, Kaste SC, Ness KK, Krasin MJ, Xie L, Wilson CL, Srivastava D, Jay DW, Davidoff AM, Zahr RS, Taneja S, Shelton KC, Lanctot JQ, Dixon SB, Ehrhardt MJ, Mulrooney DA, Armstrong GT, Robison LL, Hudson MM
Serum proteins predict treatment-related cardiomyopathy among survivors of childhood cancer
Poudel S, Shrestha H, Pan Y, Li Q, Im C, Dixon SB, Ehrhardt M, Mulrooney DA, Zhou S, Tan H, High AA, Burridge P, Bhatia S, Jefferies JL, Ness KK, Hudson MM, Robison LL, Armstrong GT, Peng J, Ky B, Yasui Y, Sapkota Y
Sexual dysfunction among long-term survivors of Hodgkin lymphoma.
Hanzlik E, Sabin ND, Yoshida T, Delaney A, Xie L, Darji H, Srivastava D, Mulrooney DA, Hudson MM, Krull KR, Khan RB
The accuracy of estimating equations for the evaluation of kidney function in adult survivors of unilateral, nonmetastatic, non-syndromic Wilms tumor: A pilot study from the St. Jude Lifetime Cohort Study
Green DM, Wang M, Krasin MJ, Davidoff AM, Srivastava D, Jay DW, Ness KK, Shulkin BL, Lanctot JQ, Shelton KC, Brennan RC, Mulrooney DA, Ehrhardt MJ, Dixon SB, Kurt BA, Robison LL, Hudson MM, Spunt SL