Cancer Survivorship Community

Apr 15, 2022

The Cancer Survivorship Community shares high quality genomic, clinical, and patient-reported data from survivors of pediatric cancer. To accelerate the rate of discovery in survivorship research we have developed this SJLIFE Survivorship Portal, a data-sharing platform for genomic and clinical data from the St. Jude Lifetime Cohort hosted on the St. Jude Cloud. The Portal features the Clinical Data Browser, GenomePaint, a genetic variant browser, for browsing, visualizing and analyzing clinical and genetic data integratively. Additionally, the Survivorship Portal will serve as a site for an expanding portfolio of risk-prediction tools developed using the SJLIFE cohort, including the recently developed Cumulative Burden Risk-Prediction Tool.

Reference: Epigenetic Age Acceleration and Chronic Health Conditions among Adult Survivors of Childhood Cancer. JNCI 2021

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Feb 03, 2024Journal of Cancer SurvivorshipPMID 38308806

Movement efficiency in survivors of childhood Acute Lymphoblastic leukemia: A report from the St. Jude Lifetime Cohort Study.

Onerup A, Mirzaei S, Wogksch MD, Goodenough CG, Lambert G, Sapkota Y, Mulrooney DA, Hudson MM, Jacola LM, Ness KK.

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Jan 24, 2024American Journal of NutritionPMID 38278365

Dietary patterns and their associations with sociodemographic and lifestyle factors in adult survivors of childhood cancer: A cross-sectional study.

Park Y, Lan T, Wang M, Ehrhardt MJ, Lanctot JQ, Jiang S, Armstrong GT, Ness KK, Hudson MM, Colditz GA, Robison LL.

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Jan 11, 2024Journal of Clinical OncologyPMID 38207238

Improved cardiomyopathy risk prediction using global longitudinal strain and N-Terminal-Pro-B-type natriuretic peptide in survivors of childhood cancer exposed to cardiotoxic therapy.

Ehrhardt MJ, Liu Q, Mulrooney DA, Rhea IB, Dixon SB, Lucas JT Jr, Sapkota Y, Shelton K, Ness KK, Srivastava DK, McDonald A, Robison LL, Hudson MM, Yasui Y, Armstrong GT.

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Jan 10, 2024Br J Haemaol

Quantitative computed tomography analysis of body composition changes in pediatric patients with Acute Lymphoblastic leukemia

Suwannaying K, Ong AA, Dhaduk R, Pei D, Iijima M, Merkle E, Zhuang TZ, Goodenough CG, Brown J, Browne EK, Wolcott B, Cheng C, Wilson CL, Pui CH, Ness KK, Kaste SC, Inaba H.

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Dec 13, 2023Stat MedPMID 38088465

Association analysis of self-reported outcomes with a validated subset

Mirzaei S, Martínez JM, Chow EJ, Ness KK, Hudson MM, Armstrong GT, Yasui Y.

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Dec 05, 2023CancerPMID 38100563

Financial hardship among siblings of long-term survivors of childhood cancer: A Childhood Cancer Survivor Study report.

Ohlsen TJD, Wang H, Buchbinder D, Huang IC, Desai AD, Zheng Z, Kirchhoff AC, Park ER, Krull K, Conti RM, Yasui Y, Leisenring W, Armstrong GT, Yabroff KR, Nathan PC, Chow EJ.

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Dec 05, 2023Pediatric Blood and CancerPMID 38053241

Job lock among survivors of childhood cancer and their spouses post Affordable Care Act implementation: A Childhood Cancer Survivor Study brief report

Waters, Austin R.; Liu, Qi, Ji Xu;Yasui, Yutaka; Yabroff, K. Robin; Conti, Rena M.; Henderson, Tara; Huang, I-Chan; Leisenring, Wendy; Armstrong, Gregory T. A; Nathan, Paul C.; Park, Elyse; Kirchhoff, Anne C.

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Dec 04, 2023J Natl Cancer Inst .PMID 38048603

Association of hearing loss with patient-reported functional outcomes in adult survivors of childhood cancer.

Bass JK, Wang F, Thaxton ME, Warren SE, Srivastava DK, Hudson MM, Ness KK, Brinkman TM. [IN PRESS]

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Nov 27, 2023Cancer ReportsPMID 38009808

Lifestyle and subsequent meningioma in childhood cancer survivors: A report from the St. Jude Lifetime Cohort Study.

Onerup A, Mirzaei S, Bhatia S, Ware M, Joffe L, Turcotte LM, Goodenough C, Sapkota Y, Dixon SB, Wogksch M, Ehrhardt MJ, Armstrong GT, Hudson MM, Ness KK.

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Nov 08, 2023Journal of Cancer SurvivorshipPMID 37938431

Trends in physical functioning in Acute Lymphoblastic leukemia and non-Hodgkin lymphoma survivors across three decades.

Wilson CL, Bjornard KL, Partin RE, Kadan-Lottick NS, Nathan PC, Oeffinger K, Hayashi RJ, Hyun G, Armstrong G, Leisenring WM, Howell RM, Yasui Y, Dixon SB, Ehrhardt MJ, Robison LL, Ness KK

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Oct 25, 2023J Natl Cancer Inst .

Dyslipidemia and Cardiovascular Disease Among Childhood Cancer Survivors: A St. Jude Lifetime Cohort Report.

Goldberg JF, Hyun G, Ness KK, Dixon SB, Towbin JA, Rhea IB, Ehrhardt MJ, Srivastava DK, Mulrooney DA, Hudson MM, Robison LL, Jefferies JL, Rohatgi A, Armstrong GT.

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Sep 18, 2023Journal of Clinical OncologyPMID 38091552

Prediabetes and associated risk of cardiovascular events and chronic kidney disease among adult survivors of childhood cancer in the St. Jude Lifetime Cohort

Dixon SB, Wang F, Lu L, Wilson CL, Jefferies JL, Green DM, Merchant TE, Howell RM, Srivastava DK, Delaney A, Robison LL, Ness KK, Hudson MM, Chemaitilly W, Armstrong GT

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Sep 09, 2023J Natl Cancer Inst .PMID 37688569

Evolving therapies, neurocognitive outcomes and functional independence in adult survivors of childhood glioma

Chiara Papini, PhD, MPH, Sedigheh Mirzaei S., PhD, Mengqi Xing, MR, Ingrid Tonning Olsson, PhD, Peter M K de Blank, MD, MSCE, Katharine R Lange, MD, Ralph Salloum, MD, Deokumar Srivastava, PhD, Wendy M Leisenring, ScD, Rebecca M Howell, PhD, Kevin C Oeffinger, MD, Leslie L Robison, PhD, Gregory T Armstrong, MD, MSCE, Kevin R Krull, PhD, Tara M Brinkman, PhD

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Aug 04, 2023 PMID 37541849

Refining the genetic risk of breast cancer with rare haplotypes and pattern mining.

William Letsou, Fan Wang, Wonjong Moon, Cindy Im, Yadav Sapkota, Leslie L Robison, Yutaka Yasui

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May 15, 2023Psycho-oncologyPMID 37189277

Response-shift effects in childhood cancer survivors: A prospective study

I-Chan Huang, Jin-Ah Sim, DeoKumar Srivastava, Kevin R Krull, Kirsten K Ness, Leslie L Robison, Justin N Baker, Melissa M Hudson, Carolyn E Schwartz

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Apr 11, 2023Cancer Epidemiol Biomarkers and PreventionPMID 37040194

The association of neighborhood characteristics and frailty in childhood cancer survivors: A report from the St. Jude Lifetime Cohort Study

Schwartz LF, Dhaduk R, Howell CR, Brinkman TM, Ehrhardt MJ, Delaney A, Srivastava, Lanctot JQ, Armstrong GT, Robison LL, Hudson MM, Ness KK, Henderson TO.

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Apr 04, 2023Med Sci Sports ExercPMID 37093894

Cancer-Related Worry as a Predictor of 5-Year Physical Activity Level in Childhood Cancer Survivors

Ware M, Krull KR, Brinkman TM, Armstrong GT, Wilson CL, Mulrooney DA, Wang Z, Lanctot JQ, Partin RE, Shelton K, Hudson MM, Robison LL, Ness KK.

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Apr 03, 2023EClinicalMedicinePMID 37090443

Determinants of health-related quality-of-life in adult survivors of childhood cancer: Integrating personal and societal values through a health utility approach.

Horan M, Srivastava DK, Bhakta N, Ehrhardt MJ, Brinkman TM, Baker J, Yasui Y, Krull KR, Ness KK, Robison LL, Hudson MM, Huang IC.

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Apr 03, 2023Cancer DiscoveryPMID 36751942

Dynamics of age- versus therapy-related clonal hematopoiesis in long-term survivors of pediatric cancer

Hagiwara K, Natarajan S, Wang Z, Zubair H, Mulder HL, Plyler E, Thimmaiah P, Dong L, Ma X, Ness KK, Li Z, Mulrooney DA, Wilson CL, Yasui Y, Hudson MM, Easton J, Robison LL, Zhang J.

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Mar 20, 2023CancerPMID 36943740

Health Behavior Profiles in Young Survivors of Childhood Cancer: Findings from the St. Jude Lifetime Cohort Study (SJLIFE)

Webster RT, Dhaduk R, Gordon ML, Partin RE, Kunin-Batson AS, Brinkman TM, Willard VW, Allen JM, Alberts NM, Lanctot JQ, Ehrhardt MJ, Li Z, Hudson MM, Robison LL, Ness KK

Mar 16, 2023Nature CommunicationsPMID 36993649

The Genetic and Epigenetic Features of Bilateral Wilms Tumor Predisposition: A Report from the Children's Oncology Group AREN18B5-Q Study.

Murphy AJ, Cheng C, Williams J, Shaw TI, Pinto EM, Dieseldorff-Jones K, Brzezinski J, Renfro LA, Tornwall B, Huff V, Hong AL, Mullen EA, Crompton B, Dome JS, Fernandez CV, Geller JI, Ehrlich PF, Mulder H, Oak N, Maciezsek J, Jablonowski C, Fleming AM, Pichavaram P, Morton CL, Easton J, Nichols KE, Clay MR, Santiago T, Zhang J, Yang J, Zambetti GP, Wang Z, Davidoff AM, Chen X.

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Feb 08, 2023Clin EpigeneticsPMID 36855205

Distinct DNA methylation signatures associated with blood lipids as exposures or outcomes among survivors of childhood cancer: A Report from the St. Jude Lifetime Cohort

Dong Q, Chen C, Song N, Qin N, Plonski NM, Finch ER, Shelton K, Easton J, Mulder H, Plyer E, Neale G, Walker E, Li Q, Huang IC, Zhang J, Wang H, Hudson MM, Robison LL, Ness KK, Wang Z.

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Feb 07, 2023BMC Oral HealthPMID 36739372

Factors for poor oral health in long-term childhood cancer survivors

Patni T, Lee CT, Li Y, Kaste S, Zhu L, Sun R, Hudson MM, Ness KK, Neumann A, Robison LL.

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Feb 01, 2023Cancer Communication (London)PMID 36256508

Social-epigenetic mediators for racial disparities in pulmonary impairment among childhood cancer survivors

Song N, Dong Q, Chen C, Li Q, Mulder H, Plyler E, Easton J, Walker E, Olson S, Neale G, Krull KR, Srivastava DK, Ness KK, Zhang J, Hudson MM, Robison LL, Huang IC, Wang Z.

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May 04, 2021J Natl Cancer Inst .PMID 32970815

Epigenetic Age Acceleration and Chronic Health Conditions Among Adult Survivors of Childhood Cancer

Na Qin, Zhenghong Li, Nan Song, Carmen L Wilson, John Easton, Heather Mulder, Emily Plyler, Geoffrey Neale, Emily Walker, Xin Zhou, Haitao Pan 5, Melissa M Hudson, Yutaka Yasui, Leslie L Robison, Jinghui Zhang, Kirsten K Ness, Zhaoming Wang