Neuro-Oncology Community
The Neuro-Oncology Community is a site designed to share clinical and molecular data from pediatric brain and spinal cord tumors in a visually interactive fashion that makes it more accessible and understandable to providers and researchers. Our hope is that this ever-expanding site will serve to advance the understanding and improve the treatment of these debilitating and, often, deadly diseases.
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Medulloblastoma patients were stratified into average-risk and high-risk treatment groups based on metastatic status and extent of resection as part of SJMB03. Medulloblastomas were molecularly classified into subgroups (Wingless [WNT], Sonic Hedgehog [SHH], g...
Children and infants who experienced medulloblastoma relapse donated tumor samples which were analyzed by DNA methylation array and next-generation sequencing. The primary-relapse pairs. The results below are arrayed by subgroup with age, sex and metadata pro...
St. Jude Children's Research Hospital
Cancer genomics has revealed many genes and core molecular processes that contribute to human malignancies, but the genetic and molecular bases of many rare cancers remains unclear. Genetic predisposition accounts for 5 to 10% of cancer diagnoses in children a...
St. Jude Children's Research Hospital
Fifty-six tumors previously diagnosed as High-Grade Glioma in patients younger than 5- years were re-characterized using histology, next-generation sequencing, and methylation. Through molecular interrogation of these tumors, we identified that they are biolo...
St. Jude Children's Research Hospital
Rare CNS Embryonal Tumors portal: This visualization serves as an adjunct to the St Jude Children's Research Hospital study on Rare CNS Embryonal Tumors and as a resource for the oncology community to explore. Funding was provided by American Lebanese Syrian...
St. Jude Children's Research Hospital